Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Comparative study of pathology of various organs of rhesus macaques exposed to two different doses of acute total-body radiation. [PDF]
Brink MW +7 more
europepmc +1 more source
Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
Detection of Bacterial Internalization in Lettuce (<i>Lactuca sativa</i>) Leaves Grown in Aquaponic Systems with Nile Tilapia (<i>Oreochromis niloticus</i>) Under Microbial Challenge. [PDF]
Jossefa AA +4 more
europepmc +1 more source
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Prospects for fistula technologies in the study of digestion and metabolism in birds. [PDF]
Vertiprakhov VG, Zaitsev SY.
europepmc +1 more source
Biochemistry of Animal and Vegetable Proteins [PDF]
openaire +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Correction: Comprehensive study of resveratrol associated to sulfadiazine in lymphocytes infected with Toxoplasma gondii: involvement of purinergic signaling in immune response. [PDF]
Bottari NB +11 more
europepmc +1 more source

