Results 41 to 50 of about 377,815 (340)

Animal experimentation in Malta : regulatory processes and future perspectives [PDF]

open access: yes, 2009
Prior to Malta’s accession to the European Union (EU) in May 2004, new legislative processes regulating the use of animals for scientific research purposes were adopted in line with the provisions found under the European Union Council Directive 86/609 ...
Scerri, Charles
core  

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Animal Experimentation in Oncology and Radiobiology: Arguments for and Against Following a Critical Literature Review

open access: yesCanadian Journal of Bioethics, 2022
Despite the international 3Rs principles that recommends replacing, reducing and refining the use of animals in medical experimentation, it remains difficult to obtain funding in Canada for medical research that respects these principles, particularly ...
William-Philippe Girard   +2 more
doaj   +1 more source

Atmosphere Behavior in Gas-Closed Mouse-Algal Systems: An Experimental and Modelling Study [PDF]

open access: yes, 1985
A dual approach of mathematical modelling and laboratory experimentation aimed at examining the gas exchange characteristics of artificial animal/plant systems closed to the ambient atmosphere was initiated.
Averner, M. M.   +3 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

The mechanical control of bushpig, Patamochoerus porcus, in Zimbabwe [PDF]

open access: yes, 1986
Bushpig, Potamocheorus porcus, occurring naturally in the high rainfall areas of Zimbabwe, have become a major threat to maize producers in the country.
LaGrange, Michael
core  

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Results of experimental modeling of postoperative peritoneal adhesions

open access: yesPatologìâ, 2019
Objective: Optimization of postoperative intraabdominal adhesions modeling. Material and methods. The objects of the study were 17 mature rats of the Wistar line of both sexes weighing 200–250 g.
M. H. Melnychenko   +2 more
doaj   +1 more source

Ruminal impaction due to plastic materials - An increasing threat to ruminants and its impact on human health in developing countries [PDF]

open access: yesVeterinary World, 2018
Ruminal impaction due to plastic materials is a condition, in which indigestible plastic foreign bodies accumulate in the rumen of ruminants leading to ruminal impaction, indigestion, recurrent tympany, and many other adverse health effects. It is caused
M. Priyanka, S. Dey
doaj   +1 more source

Moralność naukowców eksperymentujących na zwierzętach [PDF]

open access: yes, 2015
Aside from the local (mostly Western) efforts to subject animal experimentation to public scrutiny, the extent of animal experimentation, the acceptance of alternative methods and the fate of animals in laboratories depend on experimenters’ morality (as ...
Elżanowski, Andrzej
core  

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