Results 61 to 70 of about 3,107,608 (303)

Developmental Disorders in Children Recently Diagnosed With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neurocognitive deficits in adult survivors of childhood cancer are well established, but less is known about developmental disorders (DD) arising shortly after cancer diagnosis. Using 2016–2019 linked Ohio cancer registry and Medicaid data, we compared DD among 324 children with cancer and 606,913 cancer‐free controls.
Jamie Shoag, Long Vu, Ritika Miryala, Jeffrey M. Albert, Molly McVoy, Siran M. Koroukian   +5 more
wiley   +1 more source

Diosmetin Delays In Vitro Aging of Porcine Oocytes by Improving Mitochondrial Function and Reducing Oxidative Stress

Animals
Oocyte quality is crucial for successful fertilization and subsequent embryonic development. Post-ovulatory aging leads to reduced oocyte quality and impaired embryogenesis, representing an unavoidable challenge in terms of certain assisted reproductive ...
Jia-Jun Ren, Xiu-Wen Yuan, Yu-Hao Zhang, Zi-Long Meng, Xing-Wei Liang, Nam-Hyung Kim, Yong-Nan Xu, Ying-Hua Li   +7 more
doaj   +1 more source

Development and validation of Triticum phytobiological method as an alternative procedure for investigating in vivo acute toxicity on mice [PDF]

, 2017
The goal of this study was to validate an alternative method for determining in vivo acute toxicity using vegetal material instead of laboratory animals, starting from the phytobiological method known also as the Triticum technique.
Anghel, Adriana, Chiriță, Cornel, Cristea, Aurelia N., Dinu, Mihaela, Olaru, Octavian, Ştefănescu, Emil   +5 more
core   +4 more sources

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

A compact, versatile drug-induced splicing switch system with minimal background expression

Cell Reports: Methods
Summary: Gene-switch techniques hold promising applications in contemporary genetics research, particularly in disease treatment and genetic engineering.
Yue Chi, Xuan Lu, Shuangpeng Li, Jinling Wang, Jiahui Xi, Xiaoqing Zhou, Chengcheng Tang, Min Chen, Hui Yuan, Shuo Lin, Yingying Xiao, Liangxue Lai, Qingjian Zou   +12 more
doaj   +1 more source

miR-146a-5p Plays an Oncogenic Role in NSCLC via Suppression of TRAF6

Frontiers in Cell and Developmental Biology, 2020
Non-small cell lung cancer (NSCLC) is the most deadly cancer in the world due to its often delayed diagnosis. Identification of biomarkers with high sensitivity, specificity, and accessibility for early detection, such as circulating microRNAs, is ...
Xiangdong Liu, Xiangdong Liu, Xiangdong Liu, Bo Liu, Bo Liu, Bo Liu, Ruihua Li, Fei Wang, Fei Wang, Fei Wang, Ning Wang, Ning Wang, Ning Wang, Maihe Zhang, Maihe Zhang, Maihe Zhang, Yang Bai, Yang Bai, Yang Bai, Jin Wu, Jin Wu, Jin Wu, Liping Liu, Liping Liu, Liping Liu, Dongyu Han, Dongyu Han, Dongyu Han, Zhiguang Li, Bin Feng, Guangbiao Zhou, Shujing Wang, Shujing Wang, Li Zeng, Li Zeng, Li Zeng, Jian Miao, Yiqun Yao, Bin Liang, Lin Huang, Lin Huang, Qi Wang, Yingjie Wu, Yingjie Wu, Yingjie Wu, Yingjie Wu, Yingjie Wu   +46 more
doaj   +1 more source

Predicting the Future Burden of Renal Replacement Therapy in Türkiye Using National Registry Data and Comparative Modeling Approaches

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic kidney disease is a growing public health problem worldwide, and the number of patients requiring renal replacement therapy is steadily increasing. Türkiye has experienced a similar rise in both the incidence and prevalence of renal replacement therapy over the past decades; however, national‐level projections of future ...
Arzu Akgül, Neriman Sıla Koç, Berrak Itır Aylı   +2 more
wiley   +1 more source

Pharmacokinetics of Repeated Oral Dosing with Coenzyme Q10 in Cavalier King Charles Spaniels with Myxomatous Mitral Valve Disease

Antioxidants, 2020
Coenzyme Q10 (Q10) is a mitochondrial cofactor and an antioxidant with the potential to combat oxidative stress in heart failure. This study aims to determine the pharmacokinetics of repeated oral dosing of Q10 in Cavalier King Charles Spaniels (CKCS ...
Liselotte B. Christiansen, Malene K. Morsing, Maria Josefine Reimann, Torben Martinussen, Zita Birlie, Anne Marie V. Schou-Pedersen, Jens Lykkesfeldt, Lisbeth H. Olsen   +7 more
doaj   +1 more source

Quality of Reporting and Adherence to ARRIVE Guidelines in Animal Studies for Chagas Disease Preclinical Drug Research: A Systematic Review [PDF]

, 2015
Publication of accurate and detailed descriptions of methods in research articles involving animals is essential for health scientists to accurately interpret published data, evaluate results and replicate findings. Inadequate reporting of key aspects of
García Bournissen, Facundo, Gulin, Julián Ernesto Nicolás, Rocco, Daniela Marisa   +2 more
core   +4 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source