Results 81 to 90 of about 1,621,199 (300)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Morphology and DNA sequence data reveal the presence of Globodera ellingtonae in the Andean region [PDF]
, 2014 Potato cyst nematodes, G. rostochiensis and G. pallida, are the most economically important nematode pests of potatoes worldwide and are subject to strict quarantine regulations in many countries. Globodera ellingtonae was recently described from Oregon (
Doucet, Marcelo Edmundo +4 more
core
Peritoneal adhesions after laparoscopic gastrointestinal surgery [PDF]
, 2014 Although laparoscopy has the potential to reduce peritoneal trauma and post-operative peritoneal adhesion formation, only one randomized controlled trial and a few comparative retrospective clinical studies have addressed this issue.
MAIS, VALERIO
core +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Differences between the Italian and Slovak legal systems with respect to animal protection
Veterinární Medicína, 2018 This paper provides a comparative analysis of the legal content of animal protection legislation in the Slovak Republic with that of Italian legislation.
R. Balajty +3 more
doaj +1 more source
Managing Ambiguous Amphibians: Feral Cows, People, and Place in Ukraine’s Danube Delta [PDF]
, 2018 This paper analyzes how a herd of feral cattle emerged in the core zone of Ukraine’s Danube Biosphere Reserve and why it still exists despite numerous challenges to the legality of its presence there.
Richardson, Tanya
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
‘Protective’ Adaptations of Animals [PDF]
Nature, 1932 IN a recent issue of NATURE,1 “B. P. U.” makes the following challenging statement : “The whole of the book is full of examples—most carefully collected and thoroughly analysed, and represents an array of arguments of which selectionists will find it very difficult to dispose.” Unfortunately, the book2 to which reference is made is not yet available ...
openaire +3 more sources
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source