Results 261 to 270 of about 754,514 (306)

Brazil Moves Toward the Replacement of Animal Experimentation

Alternatives to Laboratory Animals, 2019
In Brazil, efforts towards the regulatory acceptance and implementation of innovative methods to replace experimental animal use in various fields began to gather force in 2008, with the approval of Law No. 11,794/2008 (the Arouca Law). This law represented a milestone, as it created the National Council for the Control of Animal Experimentation ...
Renato Ivan, de Ávila, Marize Campos, Valadares   +1 more
openaire   +2 more sources

Human skin to replace animal tests

New Scientist, 2007
Cosmetics companies are finally developing full animal replacements for testing whether their products are likely to irritate the ...
openaire   +1 more source

[Conjunctival replacement--comparative animal experiment study].

Klinische Monatsblatter fur Augenheilkunde, 1986
In a rabbit study a new material for conjunctival reconstruction was compared to lyophilized, amniotic membranes, which have been used for a long time. Standardized conjunctival defects were covered with thin, heterologous, glutaraldehyde-treated pericardium in one group, while in the other group lyophilized amnion grafts were used.
F J, Steinkogler, R, Haddad
openaire   +1 more source

Optimum replacement rates in animal breeding

Animal Science, 1974
SUMMARYThe expected annual selection response is a function of selection intensity (i), generation interval (t) and precision (p) of breeding value estimation. These three parameters may, under certain conditions, be reduced to functions of one variable, y, the mean age of breeding animals at culling, which is a simple function of the annual ...
openaire   +1 more source

[Animal experiment, can we replace?]

Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine, 2018
Animal experiment is a subject of controversies. Some people, defenders of animals, think that it is not acceptable to use for scientific purposes at the risk of making them suffer or assert that the results obtained with animals are not transposable in the human beings.
openaire   +1 more source

In-vitro techniques: can they replace animal testing?*

Human Reproduction, 1986
In-vitro tests for the long-term safety evaluation of drugs offer certain advantages. Specific properties of drugs can be identified including mutagenic and carcinogenic effects. The mechanisms leading to toxicity can be assessed. Tissue from several species, including man, can be examined.
openaire   +2 more sources

Advances in total joint replacement in small animals

Journal of Small Animal Practice, 2012
Total joint replacement is now considered a routine surgical option for small animals with advanced joint disease. This review highlights the current state of the art in total hip, elbow and knee replacement in small animals, as well as the potential for application to other joints such as the intervertebral discs, hock and shoulder.
openaire   +2 more sources

[Diaphragm replacement. An animal experiment study].

Langenbecks Archiv fur Chirurgie, 1997
Only a few indications exist for diaphragm replacement: aplasias, tumours and accidents. The defect may be so extensive that it is impossible to close the gap. Allogenic and autologous materials are proposed for replacement of the diaphragm. The disadvantages of allogenic materials are recurrence rates of up to 20% and a high rate of malalignment of ...
G, Steinau, B, Dreuw, J, Schleef, V, Schumpelick   +3 more
openaire   +1 more source

Can animal testing be replaced?

C&EN Global Enterprise, 2022
openaire   +1 more source

Diversity and evolution of the animal virome

Nature Reviews Microbiology, 2022
Erin Harvey, Edward C Holmes
exaly