Results 11 to 20 of about 5,413,831 (314)

Refining Stereotaxic Neurosurgery Techniques and Welfare Assessment for Long-Term Intracerebroventricular Device Implantation in Rodents

Animals, 2023
Stereotaxic surgeries enable precise access to specific brain regions, being of particular interest for chronic intracerebroventricular drug delivery. However, the challenge of long-term studies at this level is to allow the implantation of drug storage ...
Ester Pérez-Martín, Almudena Coto-Vilcapoma, Juan Castilla-Silgado, María Rodríguez-Cañón, Catuxa Prado, Gabriel Álvarez, Marco Antonio Álvarez-Vega, Benjamín Fernández-García, Manuel Menéndez-González, Cristina Tomás-Zapico   +9 more
doaj   +1 more source

The History of the School of Animal Science at the University of Padova (Padua) and the Evolution of Animal Science in Italy

Agriculture, 2022
In its 800-year history, the University of Padova (Padua, Italy) has come to play an important role in the development of animal science in Italy and Europe.
Giovanni Bittante, Lucia Bailoni, Alessio Cecchinato, Luigi Gallo, Roberto Mantovani, Maurizio Ramanzin, Fabio Zampieri, Stefano Schiavon, Enrico Sturaro   +8 more
doaj   +1 more source

An Ethics Toolkit to Support Animal-Centered Research and Design

Frontiers in Veterinary Science, 2022
Designers and researchers who work with animals need to employ an array of ethical competencies to guarantee the welfare of animals taking part in animal-centered research.
Luisa Ruge, Clara Mancini
doaj   +1 more source

Animal Research in Spain: A Study of Public Perception and Attitudes

Animals, 2023
Since the time of Hippocrates in the 4th century BC, animal research has been extensively used for various purposes up to the present day. However, the use of animals for research has also been controversial for a long time.
Andrea Miguel-Batuecas, Manuel Fuertes-Recuero, David Díaz-Regañón, Gustavo Ortiz-Díez, Luis Revuelta, Juan A. De Pablo-Moreno   +5 more
doaj   +1 more source

The Ethics of Innovation: Ethical Decision-Making and Review for Field Studies and Projects Targeting Dogs and Cats

Animals, 2021
To date, independent ethical oversight of many companion animal welfare initiatives has been limited and, in some instances, inadequate. Beyond a blurred line between “innovation” and “research,” the nature of the work conducted in animal welfare ...
Valerie A. Benka
doaj   +1 more source

Identifying Key Factors for Accelerating the Transition to Animal-Testing-Free Medical Science through Co-Creative, Interdisciplinary Learning between Students and Teachers

Animals, 2022
Even with the introduction of the replacement, reduction, refinement (the three Rs) approach and promising technological developments in animal-testing-free alternatives over the past two decades, a significant number of animal tests are still performed ...
Fatima Zohra Abarkan, Anna M. A. Wijen, Rebecca M. G. van Eijden, Fréderique Struijs, Phoebe Dennis, Merel Ritskes-Hoitinga, Ingrid Visseren-Hamakers   +6 more
doaj   +1 more source

Animal Research beyond the Laboratory: Report from a Workshop on Places Other than Licensed Establishments (POLEs) in the UK

Animals, 2020
Research involving animals that occurs outside the laboratory raises an array of unique challenges. With regard to UK legislation, however, it receives only limited attention in terms of official guidelines, support, and statistics, which are ...
Alexandra Palmer, Beth Greenhough, Pru Hobson-West, Reuben Message, James N. Aegerter, Zoe Belshaw, Ngaire Dennison, Roger Dickey, Julie Lane, Jamie Lorimer, Kate Millar, Chris Newman, Kirsten Pullen, S. James Reynolds, Dominic J. Wells, Matthew J. Witt, Sarah Wolfensohn   +16 more
doaj   +1 more source

Modernizing Medical Research to Benefit People and Animals

Animals, 2022
In the context of widespread public and political concern around the use of animals in research, we sought to examine the scientific, ethical and economic arguments around the replacement of animals with New Approach Methodologies (NAMs) and to situate ...
Isobel Hutchinson, Carla Owen, Jarrod Bailey   +2 more
doaj   +1 more source

Cold stress induces colitis-like phenotypes in mice by altering gut microbiota and metabolites

Frontiers in Microbiology, 2023
IntroductionThe modernized lifestyle has been paralleled by an epidemic of inflammatory bowel disease (IBD). Excessive consumption of cold beverages is especially common among the modern humans.
Lijuan Sun, Xueying Wang, Yuankang Zou, Yixuan He, Changting Liang, Juan Li, Pu Li, Pu Li, Jianbin Zhang   +8 more
doaj   +1 more source

The brown alga Padina pavonica methanol and hexane partitions prevented depressive behavior induced by dexamethasone in mice

Research in Pharmaceutical Sciences
Background and purpose: Padina pavonica, a brown alga, displays protection against oxidative stress, neuroinflammation, and neurodegenerative disorders. Considering the beneficial effects of P.
Azadeh Mesripour, Negar Asgari, Afsaneh Yegdaneh   +2 more
doaj   +1 more source