Results 31 to 40 of about 5,413,831 (314)

Mixed radiation with different doses induces CCL17 to recruit CD8+T cell to exert anti-tumor effects in non-small cell lung cancer

Frontiers in Immunology
BackgroundDifferent doses of radiotherapy (RT) exert diverse effects on tumor immunity, although the precise irradiation method remains unknown. This study sought to elucidate the influence of combining different doses of RT with immune checkpoint ...
Liuying Huang, Duo Wang, Muchen Xu, Danqi Qian, Yulin Cao, Xiaohan Wu, Liang Ming, Junhui Tang, Zhaohui Huang, Yuan Yin, Leyuan Zhou, Leyuan Zhou, Leyuan Zhou   +12 more
doaj   +1 more source

A Handful of Details to Ensure the Experimental Reproducibility on the FORCED Running Wheel in Rodents: A Systematic Review

Frontiers in Endocrinology, 2021
A well-documented method and experimental design are essential to ensure the reproducibility and reliability in animal research. Experimental studies using exercise programs in animal models have experienced an exponential increase in the last decades ...
Daniel Garrigos, Daniel Garrigos, Marta Martínez-Morga, Marta Martínez-Morga, Angel Toval, Angel Toval, Yevheniy Kutsenko, Yevheniy Kutsenko, Alberto Barreda, Alberto Barreda, Bruno Ribeiro Do Couto, Bruno Ribeiro Do Couto, Bruno Ribeiro Do Couto, Fernando Navarro-Mateu, Fernando Navarro-Mateu, Fernando Navarro-Mateu, Fernando Navarro-Mateu, José Luis Ferran, José Luis Ferran   +18 more
doaj   +1 more source

Zebrafish as animal model for aquaculture nutrition research. [PDF]

, 2014
The aquaculture industry continues to promote the diversification of ingredients used in aquafeed in order to achieve a more sustainable aquaculture production system. The evaluation of large numbers of diets in aquaculture species is costly and requires
Feijoo, Carmen G, Medrano, Juan F, Ulloa, Pilar E   +2 more
core   +2 more sources

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

Toward an integrated ethical review process: an animal-centered research framework for the refinement of research procedures

Frontiers in Veterinary Science
The involvement of animals in research procedures that can harm them and to which they are deemed unable to consent raises fundamental ethical dilemmas.
Eleonora Nannoni, Clara Mancini
doaj   +1 more source

Exploring Research through Design in Animal-Computer Interaction [PDF]

, 2017
This paper explores Research through Design (RtD) as a potential methodology for developing new interactive experiences for animals. We present an example study from an on-going project and examine whether RtD offers an appropriate framework for ...
Dawkins M.S., French F., French F., Haraway D.J.., Locoro A., Mancini C., van der Linden D., Zimmerman J.   +7 more
core   +2 more sources

Gluconate-Lactobionate-Dextran Perfusion Solutions Attenuate Ischemic Injury and Improve Function in a Murine Cardiac Transplant Model

Cells, 2022
Static cold storage is the cheapest and easiest method and current gold standard to store and preserve donor organs. This study aimed to compare the preservative capacity of gluconate-lactobionate-dextran (Unisol) solutions to histidine-tryptophan ...
Yinan Guo, Franka Messner, Sarah E. Beck, Marcos Iglesias Lozano, Hubert Schwelberger, Yichuan Zhang, Kai Kammers, Byoung Chol Oh, Elizabeth D. Greene, Gerald Brandacher, Kelvin G. M. Brockbank   +10 more
doaj   +1 more source

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee, Holly Evans, Claire E. Wakefield, Antoinette Anazodo, Richard J. Cohn, Brittany C. McGill, Elizabeth A. Lobb, Lori Wiener, Madeleine L. Juhrmann, Ursula M. Sansom‐Daly   +9 more
wiley   +1 more source

A Proposal for a Noxious Stimuli-Free, Moderate-Intensity Treadmill Running Protocol to Improve Aerobic Performance in Experimental Research on Rats

Metabolites
Background/Objectives: Animal models can help understand human physiological responses, including the response to exercise and physical activity. However, many of these models incorporate noxious stimuli for various scientific purposes.
Gilmara Gomes de Assis, Elda Olivia Nobre de Souza, Paulo Francisco de Almeida-Neto, Halil İbrahim Ceylan, Nicola Luigi Bragazzi   +4 more
doaj   +1 more source

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song, Jonathan Baron, Carlos Chavez Perez, Sidharth Ramesh, Jane Minturn, Kavita A. Desai, Amish C. Shah, Jean M. Belasco, Kristina A. Cole, Michael J. Fisher, Phillip B. Storm, Peter M. Madsen, Goldie Kurtz, Robert A. Lustig, Christine Hill‐Kayser, Michael J. LaRiviere   +15 more
wiley   +1 more source