Results 31 to 40 of about 53,985,043 (260)

Bridging the Loneliness Gap: Depression, Connectivity, and Isolation in Pediatric Oncology Patients and Their Peers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld, Scott H. Maurer, Michelle D. Watkinson, John Nury, Elise Barberis, Molly C. Mack   +5 more
wiley   +1 more source

South Dakota Animal Disease Research & Diagnostic Laboratory: Annual Report 2014 [PDF]

, 2014
This document is the 2014 annual report of the South Dakota Veterinary and Biomedical Science Department Animal Disease Research and Diagnostic ...
Animal Disease Research and Diagnostic Laboratory, South Dakota State University
core   +1 more source

Reviewing the Review: A Pilot Study of the Ethical Review Process of Animal Research in Sweden

Animals, 2021
The use of animals in research entails a range of societal and ethical issues, and there is widespread consensus that animals are to be kept safe from unnecessary suffering.
Svea Jörgensen, Johan Lindsjö, Elin M. Weber, Helena Röcklinsberg   +3 more
doaj   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Zebrafish as an alternative animal model in human and animal vaccination research

, 2020
Much of medical research relies on animal models to deepen knowledge of the causes of animal and human diseases, as well as to enable the development of innovative therapies.
Grejo Setti, Princia, Bailone, Ricardo Lacava [UNESP], Borra, Ricardo Carneiro, Roca, Roberto De Oliveira [UNESP], De Aguiar, Luis Kluwe, Fukushima, Hirla Costa Silva, Ventura Fernandes, Bianca Helena, Correa, Tatiana, Janke, Helena   +8 more
core   +1 more source

Animal Welfare Ethics in Research and Testing: Implementation and its Barrier [PDF]

, 2020
Animals have an important role in research and testing to improve human and animal health. Animal usage must be balanced between science and ethical values of animal welfare.
Wahyuwardani, Sutiastuti, Noor, S M, Bakrie, B   +2 more
core   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

State of the Animal: monitoring animal welfare and health in The Netherlands (0-measurement) : summary, full report is available in Dutch (report 323) [PDF]

, 2010
25 measuring points summarise the results of policy measures for animal welfare and health in The ...
Ipema, A.H., Leenstra, F.R., Hanekamp, W.J.A., Vermeij, I., Verstappen-Boerekamp, J.A.M., Bergevoet, R.H.M., Neijenhuis, F., Jong, A.R.   +7 more
core  

Mixed radiation with different doses induces CCL17 to recruit CD8+T cell to exert anti-tumor effects in non-small cell lung cancer

Frontiers in Immunology
BackgroundDifferent doses of radiotherapy (RT) exert diverse effects on tumor immunity, although the precise irradiation method remains unknown. This study sought to elucidate the influence of combining different doses of RT with immune checkpoint ...
Liuying Huang, Duo Wang, Muchen Xu, Danqi Qian, Yulin Cao, Xiaohan Wu, Liang Ming, Junhui Tang, Zhaohui Huang, Yuan Yin, Leyuan Zhou, Leyuan Zhou, Leyuan Zhou   +12 more
doaj   +1 more source