Results 21 to 30 of about 5,413,831 (314)

Review of Animal Models to Study Pulp Inflammation

Frontiers in Dental Medicine, 2021
Human dental pulp is a highly dynamic tissue equipped with a network of resident immunocompetent cells that play a major role in the defense against pathogens and during tissue injury.
Davy Aubeux, Davy Aubeux, Davy Aubeux, Emmanuelle Renard, Emmanuelle Renard, Emmanuelle Renard, Fabienne Pérez, Fabienne Pérez, Fabienne Pérez, Solène Tessier, Solène Tessier, Valérie Geoffroy, Valérie Geoffroy, Alexis Gaudin, Alexis Gaudin, Alexis Gaudin   +15 more
doaj   +1 more source

Quality and validity of large animal experiments in stroke : a systematic review [PDF]

, 2020
An important factor for successful translational stroke research is study quality. Low-quality studies are at risk of biased results and effect overestimation, as has been intensely discussed for small animal stroke research.
Bahor, Z., Boltze, Johannes, Herrmann, A. M., Kringe, L., Meckel, S., Motschall, E., Mülling, C., Sena, E. S., Wang, Q.   +8 more
core   +4 more sources

How to optimize communication about animal and animal-free research methods

Frontiers in Veterinary Science
There is a long-standing debate about experimental non-human animals and animal-free methods in scientific research. Among the various stakeholders involved in the debate are the scientists.
Judith Regina Homberg, Aldert H. Piersma, Aldert H. Piersma, Cyrille A. M. Krul, Lisa Genzel, Anne Kienhuis, Ellen ter Gast, Monique Wolvekamp   +7 more
doaj   +1 more source

Current Directions in the Auricular Vagus Nerve Stimulation I – A Physiological Perspective

Frontiers in Neuroscience, 2019
Electrical stimulation of the auricular vagus nerve (aVNS) is an emerging technology in the field of bioelectronic medicine with applications in therapy.
Eugenijus Kaniusas, Stefan Kampusch, Stefan Kampusch, Marc Tittgemeyer, Marc Tittgemeyer, Fivos Panetsos, Raquel Fernandez Gines, Michele Papa, Attila Kiss, Bruno Podesser, Antonino Mario Cassara, Emmeric Tanghe, Amine Mohammed Samoudi, Thomas Tarnaud, Wout Joseph, Vaidotas Marozas, Arunas Lukosevicius, Niko Ištuk, Antonio Šarolić, Sarah Lechner, Wlodzimierz Klonowski, Giedrius Varoneckas, Giedrius Varoneckas, Jozsef Constantin Széles   +23 more
doaj   +1 more source

Reviewing the Review: A Pilot Study of the Ethical Review Process of Animal Research in Sweden

Animals, 2021
The use of animals in research entails a range of societal and ethical issues, and there is widespread consensus that animals are to be kept safe from unnecessary suffering.
Svea Jörgensen, Johan Lindsjö, Elin M. Weber, Helena Röcklinsberg   +3 more
doaj   +1 more source

Dexamethasone for Chemotherapy‐Induced Nausea and Vomiting Prevention in Pediatric Patients: International Consensus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An international Delphi panel of experts developed consensus statements to delineate the circumstances where the risks of dexamethasone as an antiemetic do and do not outweigh its benefits. Procedure Experts in supportive care of pediatric patients were invited to participate.
Negar Shavandi, Paula D. Robinson, Shana Jacobs, L. Lee Dupuis, the International Pediatric Dexamethasone Panel, Sameer Bakhshi, Tiene Bauters, Eva Brack, Simone Cesaro, Claire Fosbrook, Jason Freedman, Tamara MacDonald, Eloise Neumann, Venkatraman Radhakrishnan, Rod Rassekh, Florian Slimano, Johnathan Soggee, Joel Thompson, Marianne van de Wetering, Milena Villarroel, Jasper Wong   +20 more
wiley   +1 more source

Real‐World Pediatric Blinatumomab Administration: Access to Outpatient Care Delivery and Impact of a Hospital‐Dispensed Model

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Blinatumomab has been shown to be highly effective for patients with pediatric B‐ALL and has recently become standard of care therapy. Due to its past use in the clinical trial setting, there is limited information available about real‐world administration.
Katelyn Oranges, Kelly A. Duffy, Sara McDonough, Evelyn Kurpiewski, R. Jennifer Randall, Allison Barz Leahy, Haley M. Newman, Joyce P. Lee, Stephen P. Hunger, Anne F. Reilly, David T. Teachey, Susan R. Rheingold, Daniel J. Zheng   +12 more
wiley   +1 more source

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Survival-Span Method: How to Qualitatively Estimate Lifespan to Improve the Study of Aging, and not Disease, in Aging Studies

Frontiers in Aging, 2021
Lifespan analyses are important for advancing our understanding of the aging process. There are two major issues in performing lifespan studies: 1) late-stage animal lifespan analysis may include animals with non-terminal, yet advanced illnesses, which ...
Julia Adelöf, Jaime M. Ross, Jaime M. Ross, Madeleine Zetterberg, Madeleine Zetterberg, Malin Hernebring, Malin Hernebring   +6 more
doaj   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source