Results 251 to 260 of about 284,210 (304)

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

Using Risk-Benefit Analysis and the Analytical Hierarchy Process to Decide on the Implementation of Rapid Salmonella Detection Methods in Large Poultry Industries. [PDF]

Risk Anal
Magalhães CRP, de Aquino NSM, Tondo EC.
europepmc   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Bench to bedside: Bridging the gap. [PDF]

Indian J Ophthalmol
Steel CL, Wirostko BM.
europepmc   +1 more source

Institutional animal care and use committees and the challenges of evaluating animal research proposals. [PDF]

Res Integr Peer Rev
Pippin JJ, Bailey J, Kennedy M, Press DD, McCarthy J, Baron R, Farghali S, Baker E, Barnard ND.   +8 more
europepmc   +1 more source

Consumer Acceptance of Sustainable Cat Diets: A Survey of 1380 Cat Guardians. [PDF]

Animals (Basel)
Mace JL, Bauer A, Knight A, Nicholles B.
europepmc   +1 more source

Perspective of using <i>in vitro</i> models to understand immunotherapy-induced cytokine release syndrome. [PDF]

Front Immunol
Perkins E, Cooper C, Lund E, Alb M, Morgan H, Fogal B, Hewitt P, Mazein A, Ostaszewski M, Sewald K.   +9 more
europepmc   +1 more source

Revision of the Choices Nutrient Profiling System. [PDF]

Nutrients
Smorenburg H, Kissock KR, Beck EJ, Mathur P, Hamaker B, Lissner L, Marostica MR, Nnam N, Takimoto H, Roodenburg AJC.   +9 more
europepmc   +1 more source

Sensitivity analysis of censored output through polynomial, logistic and tobit models: Theory and case study. [PDF]

Kleijnen, J.P.C., Nielen, M., Vonk Noordegraaf, A.   +2 more
core   +1 more source