Results 271 to 280 of about 284,210 (304)

Trend on alternative to animal testing

International Journal of Cosmetic Science, 2007
For the promotion of 3R's (Reduction, Refinement and Replacement) principles of animal tests, the EU and US established the European Center for the Validation of Alternative Methods (ECVAM) and the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM), respectively.
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[Alternatives to animal testing].

Bulletin de l'Academie nationale de medecine, 2010
The use of alternative methods to animal testing are an integral part of the 3Rs concept (refine, reduce, replace) defined by Russel & Burch in 1959. These approaches include in silico methods (databases and computer models), in vitro physicochemical analysis, biological methods using bacteria or isolated cells, reconstructed enzyme systems, and ...
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Advancing alternative methods to reduce animal testing

Science
Emerging approaches show promise for regulatory ...
Chad P, Nelson, Paul, Brown, Suzanne, Fitzpatrick, Kevin A, Ford, Paul C, Howard, Tracy, MacGill, Edward E C, Margerrison, Jacqueline, O'Shaughnessy, Tucker A, Patterson, Rakesh, Raghuwanshi, Rodney, Rouse, Selen, Stromgren, Kyung E, Sung, Luis G, Valerio, Jeffrey L, Ward, Namandjé N, Bumpus   +15 more
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The Johns Hopkins Center for Alternatives to Animal Testing

Toxicological Sciences, 1984
The Center strives to develop new non-whole-animal test methodologies based on understanding mechanisms of toxicity of chemicals, consumer products, and drugs for the evaluation of safety. The Center will strive for scientific excellence, and to provide superior methods which will replace existing strategies.
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The new paradigm in animal testing – “3Rs alternatives”

Regulatory Toxicology and Pharmacology
Regulatory studies have revolutionised over time. Today, the focus has shifted from animal toxicity testing to non-animal for regulatory safety testing. This move is in line with the international 3Rs (Replacement, Reduction, and Refinement) principle and has also changed the regulator's perspective.
Wen Tsin, Poh, Johnson, Stanslas
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Alternatives to Animals in Toxicity Testing

Scientific American, 1989
A M, Goldberg, J M, Frazier
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The use of alternatives to animal tests in developing countries.

Developments in biological standardization, 1999
Consideration of alternative methods for animal tests in developing countries is important because good quality laboratory animals and proper animal facilities are not always sufficiently available to perform the currently required quality control tests.
Hong, HA, Hendriks, J
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Welcome Alternatives to Animal Testing

Genetic Engineering & Biotechnology News, 2021
Gary Michelson, Aysha Akhtar
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Human skin equivalent as an alternative to animal testing.

GMS Krankenhaushygiene interdisziplinar, 2008
The 3-D skin equivalent can be viewed as physiologically comparable to the natural skin and therefore is a suitable alternative for animal testing. This highly differentiated in vitro human skin equivalent is used to assess the efficacy and mode of action of novel agents.
Mertsching, H, Weimer, M, Kersen, S, Brunner, H   +3 more
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Alternatives to ocular irritation testing in animals.

Lens and eye toxicity research, 1993
The preliminary conclusions of a survey of possible non-animal alternatives to the Draize rabbit eye irritancy test, recently conducted for the Commission of the European Communities, are presented. The various types of alternatives to animal tests are reviewed in terms of their current state of development and validation, and also their potential in ...
K A, Atkinson, J H, Fentem, R H, Clothier, M, Balls   +3 more
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