Results 1 to 10 of about 1,488 (106)
Exposomics: a review of methodologies, applications, and future directions in molecular medicine [PDF]
EMBO Molecular MedicineThe exposome is the measure of all the exposures of an individual in a lifetime and how those exposures relate to health. Exposomics is the emerging field of research to measure and study the totality of the exposome. Exposomics can assist with molecular
Melissa Wan +2 more
exaly +3 more sources
Exposomics as a discovery engine for emerging contaminants and hidden biological risks
Emerging ContaminantsOver the past decade, exposome science has evolved from a conceptual framework into a practical discovery engine for environmental health. By combining high-resolution mass spectrometry, non-targeted analysis, multi-omics integration, wearable sensors ...
Oluwatobi Kolawole +2 more
doaj +2 more sources
Metabolites, 2022 Extracting metabolic features from liquid chromatography-mass spectrometry (LC-MS) data has been a long-standing bioinformatic challenge in untargeted metabolomics.
Sam Shen, Brian Low, Yaxi Hu
exaly +3 more sources
AI redefine untargeted metabolomics: estimating chemical amounts for a Human Exposome Project [PDF]
Frontiers in Public HealthThe Human Exposome Project aims to map the totality of environmental exposures, but its success relies on transforming qualitative detections into quantitative data.
Fenna C. M. Sillé +8 more
doaj +2 more sources
CCDB: A database for exploring inter-chemical correlations in metabolomics and exposomics datasets
Environment International, 2022 Inter-chemical correlations in metabolomics and exposomics datasets provide valuable information for studying relationships among chemicals reported for human specimens.
Dinesh Kumar Barupal, , Manish Arora
exaly +3 more sources
Frontiers in Toxicology, 2023 Introduction: The positive identification of xenobiotics and their metabolites in human biosamples is an integral aspect of exposomics research, yet challenges in compound annotation and identification continue to limit the feasibility of comprehensive ...
Emily Golden +2 more
exaly +3 more sources
Molecules, 2022 Pooled quality controls (QCs) are usually implemented within untargeted methods to improve the quality of datasets by removing features either not detected or not reproducible.
Gianfranco Frigerio +2 more
exaly +3 more sources
Big Data, epistemology and causality: Knowledge in and knowledge out in EXPOsOMICS
Big Data and Society, 2016 Recently, it has been argued that the use of Big Data transforms the sciences, making data-driven research possible and studying causality redundant. In this paper, I focus on the claim on causal knowledge by examining the Big Data project EXPOsOMICS ...
Stefano Canali
exaly +2 more sources
Advancing translational exposomics: bridging genome, exposome and personalized medicine [PDF]
Human GenomicsUnderstanding the interplay between genetic predisposition and environmental and lifestyle exposures is essential for advancing precision medicine and public health. The exposome, defined as the sum of all environmental exposures an individual encounters
Dimosthenis Sarigiannis +9 more
doaj +2 more sources
LifeWe are exposed to a mixture of environmental man-made and natural xenobiotics. We experience a wide spectrum of environmental exposure in our lifetime, including the effects of xenobiotics on gametogenesis and gametes that undergo fertilization as the ...
Anca-Narcisa Neagu +2 more
exaly +3 more sources