Results 11 to 20 of about 2,584 (204)
LifeWe are exposed to a mixture of environmental man-made and natural xenobiotics. We experience a wide spectrum of environmental exposure in our lifetime, including the effects of xenobiotics on gametogenesis and gametes that undergo fertilization as the ...
Costel C Darie
exaly +5 more sources
Analytical challenges and opportunities in the study of endocrine disrupting chemicals within an exposomics framework [PDF]
Talantahuman body. Exposome-scale studies have significant potential to understand the interplay of environmental factors with complex multifactorial diseases widespread in our society and whose origin remain unclear.
Jesús Marín-Sáez +2 more
exaly +4 more sources
Advancing Dose-Response Research: Integrating Exposome, Multi-Omics, and Low-Dose Phenomena in Toxicology and Medicine [PDF]
Dose-ResponseThe field of dose-response research has evolved dramatically, propelled by advancements in exposomics concept, multi-omics technologies, and a growing appreciation of low-dose effects across disciplines.
Lu Cai
doaj +2 more sources
Fin Whale as a Sink of Legacy and Emerging Contaminants: First Integrated Chemical Exposomics and Gene Expression Analysis in Cetaceans. [PDF]
Environ Sci TechnolCetaceans face numerous anthropogenic chemical stressors in global oceans, yet there is a lack of studies that simultaneously assess their cumulative exposure to both legacy and emerging contaminants and their combined effects.
Fossi MC +8 more
europepmc +3 more sources
GC vitamin D-binding protein gene functional genetic variants and gestational diabetes mellitus risk and prediction [PDF]
Scientific ReportsGestational diabetes mellitus (GDM) is a pregnancy-complicated disease that poses risks to maternal and infant health. However, its etiology has not yet been elucidated.
Ruiqi Li +7 more
doaj +2 more sources
Current Environmental Health Reports, 2015 The exposome concept takes a holistic approach facilitated by new and emerging technologies to describe 'the totality of human environmental (i.e. non-genetic) exposures from conception onwards, complementing the genome'. It provides a framework to advance the environmental epidemiology field that has until now focused almost exclusively on single ...
Oliver, Robinson, Martine, Vrijheid
openaire +3 more sources
Metabolites, 2022 Extracting metabolic features from liquid chromatography-mass spectrometry (LC-MS) data has been a long-standing bioinformatic challenge in untargeted metabolomics.
Jian Guo +11 more
doaj +1 more source
Myc-Associated Zinc Finger Protein Promotes Metastasis of Papillary Thyroid Cancer
Frontiers in Bioscience-Landmark, 2023 Background: Myc-associated zinc finger protein (MAZ) plays a role in cancer progression and metastasis. However, the role and underlying molecular mechanism of MAZ in thyroid cancer have not yet been fully elucidated.
Chuanjun Zheng +9 more
doaj +1 more source
Migrasomes and tetraspanins in hepatocellular carcinoma: current status and future prospects
Future Science OA, 2023 In recent years, many studies have attempted to clarify the formation, structure and biological function of migrasomes, which are defined as specialized organelles formed by the tips and intersections of Retraction Fibrils during cell migration.
Zhongqi Zhang +4 more
doaj +1 more source
Human exposome assessment platform
Environmental Epidemiology, 2021 The Human Exposome Assessment Platform (HEAP) is a research resource for the integrated and efficient management and analysis of human exposome data. The project will provide the complete workflow for obtaining exposome actionable knowledge from population-based cohorts.
Merino Martinez, Roxana +22 more
openaire +5 more sources