Reconceptualizing and Defining Exposomics within Environmental Health: Expanding the Scope of Health Research [PDF]
Environmental Health PerspectivesCaspar Safarlou +2 more
exaly +2 more sources
Untargeted lipidomic features associated with colorectal cancer in a prospective cohort. [PDF]
, 2018 BackgroundEpidemiologists are beginning to employ metabolomics and lipidomics with archived blood from incident cases and controls to discover causes of cancer.
Cai, Xiaoming +11 more
core +3 more sources
What Is New about the Exposome? Exploring Scientific Change in Contemporary Epidemiology [PDF]
, 2020 In this commentary, I discuss the scientific changes brought by the exposome, asking what is new about this approach and line of research. I place the exposome in a historical perspective, by analyzing the conditions under which the exposome has been ...
Canali, Stefano
core
Towards a comprehensive characterisation of the human internal chemical exposome: Challenges and perspectives [PDF]
, 2021 The holistic characterisation of the human internal chemical exposome using high-resolution mass spectrometry (HRMS) would be a step forward to investigate the environmental AE tiology of chronic diseases with an unprecedented precision.
Aalizadeh +130 more
core +3 more sources
Chemical Isotope Labeling Exposome (CIL-EXPOSOME): One High-Throughput Platform for Human Urinary Global Exposome Characterization [PDF]
Environmental Science & Technology, 2019 Human exposure to hundreds of chemicals, a primary component of the exposome, has been associated with many diseases. Urinary biomarkers of these chemicals are commonly monitored to quantify their exposure. However, because of low concentrations and the great variability in physicochemical properties of exposure biomarkers, exposome research has been ...
Shenglan Jia +6 more
openaire +4 more sources
Effects of exposure to water disinfection by-products in a swimming pool: A metabolome-wide association study [PDF]
, 2017 BACKGROUND: Exposure to disinfection by-products (DBPs) in drinking water and chlorinated swimming pools are associated with adverse health outcomes, but biological mechanisms remain poorly understood ...
Barupal, Dinesh Kumar +14 more
core +1 more source
Defining the Scope of Exposome Studies and Research Needs from a Multidisciplinary Perspective [PDF]
, 2021 The concept of the exposome was introduced over 15 years ago to reflect the important role that the environment exerts on health and disease. While originally viewed as a call-to-arms to develop more comprehensive exposure assessment methods applicable ...
Carlsten, Christopher +17 more
core +2 more sources
Metabolites, 2022 Exposomics analyses have highlighted the importance of biomonitoring of human exposure to pollutants, even non-persistent, for the prevention of non-communicable diseases such as obesity, diabetes, non-alcoholic fatty liver disease, atherosclerosis, and ...
Fabrizia Carli +2 more
doaj +1 more source
The role of mycotoxins in the human exposome: Application of mycotoxin biomarkers in exposome-health studies [PDF]
, 2018 Mycotoxins are secondary metabolites produced by fungi that may contaminate different foods intended for human consumption, resulting in a widespread exposure worldwide. The novel exposome paradigm has the ambition to decipher the different environmental
Cano Sancho, German +3 more
core +4 more sources
Journal of Dermatological Science, 2017 The term "exposome" describes the totality of exposures to which an individual is subjected from conception to death. It includes both external and internal factors as well as the human body's response to these factors. Current exposome research aims to understand the effects all factors have on specific organs, yet today, the exposome of human skin ...
Krutmann, Jean +4 more
openaire +2 more sources