Results 51 to 60 of about 2,584 (204)

From John Snow to omics: the long journey of environmental epidemiology

, 2018
A major difference between infectious and non-communicable diseases is that infectious diseases typically have unique necessary causes whereas noncommunicable diseases have multiple causes which by themselves are usually neither necessary nor sufficient.
Vineis, P
core   +1 more source

Human Early Life Exposome (HELIX) study: a European population-based exposome cohort [PDF]

BMJ Open, 2018
PurposeEssential to exposome research is the collection of data on many environmental exposures from different domains in the same subjects. The aim of the Human Early Life Exposome (HELIX) study was to measure and describe multiple environmental exposures during early life (pregnancy and childhood) in a prospective cohort and associate these exposures
Maitre, Léa, De Bont, Jeroen, Casas, Maribel, Robinson, Oliver, Aasvang, Gunn Marit, Agier, Lydiane, Andrušaitytė, Sandra, Ballester, Ferrán, Basagaña, Xavier, Borrás, Eva, Brochot, Céline, Bustamante, Mariona, Carracedo, Angel, De Castro, Montserrat, Dedele, Audrius, De Castro, Montserrat, Dedele, Audrius, Donaire González, David, Estivill, Xavier, Evandt, Jorunn, Fossati, Serena, Giorgis Allemand, Lise, Granum, Berit, Grazuleviciene, Regina, Gützkow, Kristine Bjerve, Småstuen Haug, Line, Hernández Ferrer, Carles, Heude, Barbara, Ibarluzea Maurolagoitia, Jesús María, Julvez, Jordi, Karachaliou, Marianna, Keun, Hector C, Hjertager Krog, Norun, Lau, Chung-Ho E., Leventakou, Vasiliki, Lyon Caen, Sarah, Manzano, Cyntia, Mason, Dan, McEachan, Rosemary, Meltzer, Helle Margrete, Petraviciene, Inga, Quentin, Joane, Roumeliotaki, Theano, Sabido, Eduard, Saulnier, Pierre-Jean, Siskos, Alexandros P, Siroux, Valérie, Sunyer, Jordi, Tamayo, Ibon, Urquiza, Jose, Vafeiadi, Marina, Van Gent, Diana, Vives Usano, Marta, Waiblinger, Dagmar, Warembourg, Charline, Chatzi, Leda, Coen, Muireann, Van den Hazel, Peter, Nieuwenhuijsen, Mark J., Slama, Rémy, Thomsen, Cathrine, Wright, John, Vrijheid, Martine   +62 more
openaire   +13 more sources

Médecine personnalisée versus médecine de la personne : une fausse alternative [PDF]

, 2017
Personalized medicine has recently become the new horizon of healthcare policies worldwide, but it has also given rise to misunderstandings and conflicting debates due to the lack of clear definitions and appropriate framing.
Guchet, Xavier
core   +2 more sources

Puerarin Prevents Bisphenol S Induced Lipid Accumulation by Reducing Liver Lipid Synthesis and Promoting Lipid Metabolism in C57BL/6J Mice

Toxics, 2023
Bisphenol S (BPS) is an environmental pollutant that can accumulate in the human body and cause harm. Puerarin (PUE) is a flavonoid with anti-inflammatory and antioxidant effects.
Zi-Yao Wu, Li Luo, Ya-Qi Kan, Mei-Lin Qin, Hai-Ting Li, Qing-Zhi He, Huai-Cai Zeng   +6 more
doaj   +1 more source

Concentrations and gas-particle partitioning of PCDD/Fs in the urban air of Dalian, China [PDF]

, 2012
PCDD/Fs in the urban air of Dalian, China were monitored with high-volume active sampler from November 2009 to October 2010. The concentration of Cl4-8DD/Fs ranged from 3065 to 49538 fg m(-3), with an average of 10249 fg m(-3).
JiPing Chen, Jun Mu, Karl-Werner Schramm, Qian Xu, SongTao Qin, Wei Wang, XiaoXiao Li, XiuHua Zhu, YuWen Ni   +8 more
core   +1 more source

Utilizing a biology-driven approach to map the exposome in health and disease:An essential investment to drive the next generation of environmental discovery [PDF]

, 2021
BACKGROUND: Recent developments in technologies have offered opportunities to measure the exposome with unprecedented accuracy and scale. However, because most investigations have targeted only a few exposures at a time, it is hypothesized that the ...
Chung, M.K., dIRAS RA-2, IRAS OH Epidemiology Chemical Agents, Miller, G.W., Nguyen, V.K., Patel, C.J., Rappaport, S.M., van der Meer, T.P., Vermeulen, R., Wheelock, C.E.   +9 more
core   +2 more sources

Exposomics as a discovery engine for emerging contaminants and hidden biological risks

Emerging Contaminants
Over the past decade, exposome science has evolved from a conceptual framework into a practical discovery engine for environmental health. By combining high-resolution mass spectrometry, non-targeted analysis, multi-omics integration, wearable sensors ...
Oluwatobi Kolawole, Atallah Elzein, Tim Marczylo   +2 more
doaj   +1 more source

Precision public health in the making: examining the becoming of the "social" in a Swiss environmental health population-based cohort. [PDF]

, 2023
Expanding the concept of "precision" or "personalized" medicine, personalized health and precision public health designate the use of various kinds of data-genomic, other omics, clinical, or those produced by individuals themselves through self-tracking ...
Bühler, N.
core   +1 more source

MAZ-mediated N6-methyladenosine modification of ZEB1 promotes hepatocellular carcinoma progression by regulating METTL3

Journal of Translational Medicine
Background Hepatocellular carcinoma (HCC) has a hidden onset and high malignancy. Its high metastasis, high recurrence, and short survival time have always been a difficult and hot spot in clinical practice.
Di Li, Li Xu, Ruyuan Liu, Zhaonv Yao, Chuanjun Zheng, Song Jin, Xuefeng Guo, Zhengbao Zhang, Shengkui Tan, Xiaonian Zhu   +9 more
doaj   +1 more source

Pollutants in Microenvironmental Cellular Interactions During Liver Inflammation Cancer Transition and the Application of Multi-Omics Analysis

Toxics
This study categorizes pollutant-induced inflammation–cancer transition into three stages: non-alcoholic fatty liver disease (NAFLD), liver fibrosis, and hepatocellular carcinoma (HCC).
Yulun Jian, Yuhan Li, Yanfeng Zhou, Wei Mu   +3 more
doaj   +1 more source