Results 31 to 40 of about 1,965 (197)

Introduction to Exposomics [PDF]

, 2019
Short course on Exposomics given at the Society of Environmental Toxicology and Chemistry (SETAC) 40th annual meeting November ...
elin ulrich (6671857)
core   +1 more source

Constructing metagenome-assembled genomes for almost all components in a real bacterial consortium for binning benchmarking

BMC Genomics, 2022
Background So far, a lot of binning approaches have been intensively developed for untangling metagenome-assembled genomes (MAGs) and evaluated by two main strategies.
Ziyao Wu, Yuxiao Wang, Jiaqi Zeng, Yizhuang Zhou   +3 more
doaj   +1 more source

Phospholipid removal for enhanced chemical exposomics in human plasma [PDF]

, 2023
The challenge of chemical exposomics in human plasma is the 1000-fold concentration gap between endogenous substances and environmental pollutants. Phospholipids are the major endogenous small molecules in plasma, thus we validated a chemical exposomics ...
Xie, Hongyu, Bonnefille, Bénilde,, Xie, Hongyu,, Sdougkou, Kalliroi,, Sdougkou, Kalliroi, Bonnefille, Bénilde, Martin, Jonathan W., Bergdahl, Ingvar, Martin, Jonathan W.,, Papazian, Stefano, Papazian, Stefano,, Bergdahl, Ingvar A.   +11 more
core   +1 more source

Chemical safety and the exposome

Emerging Contaminants, 2023
Air pollution and rapid chemical intensification are major threats to the environment and human health. Today, we have produced over 350,000 chemicals, and current testing strategies do not meet the demands. Therefore, it is important to develop new approach methodologies (NAMs) that can help fill current information gaps.
openaire   +4 more sources

Using exposomics to assess cumulative risks and promote health [PDF]

, 2015
Under the exposome paradigm all nongenetic factors contributing to disease are considered to be 'environmental' including chemicals, drugs, infectious agents, and psychosocial stress.
Martyn T. Smith, Sarah I. Daniels, de la Rosa, Rosemarie, Daniels, Sarah I, Smith, Martyn T, Rosemarie de la Rosa   +5 more
core   +1 more source

Genetic variants of ERBB4 gene and risk of gestational diabetes mellitus: a susceptibility and diagnostic nomogram study

Frontiers in Endocrinology, 2023
IntroductionGestational diabetes (GDM) is one of the common complications of female pregnancy, which seriously affects the health of mothers and their offspring.
Ruiqi Li, Yukun Wang, Lin Yang, Ping Zhong, Gongchen Huang, Qiulian Liang, Xiangyuan Yu   +6 more
doaj   +1 more source

Large scale enzyme based xenobiotic identification for exposomics. [PDF]

, 2021
Advances in genomics have revealed many of the genetic underpinnings of human disease, but exposomics methods are currently inadequate to obtain a similar level of understanding of environmental contributions to human disease.
Woodworth, Michael H, Jones, Dean P, Castellanos, Francisco, Ziegler, Thomas R, Go, Young-Mi, Bais, Preeti, Lee, Choon M, Liu, Ken H, Singer, Grant, Miller, Gary W, Kraft, Colleen S, Morgan, Edward T, Li, Shuzhao   +12 more
core   +2 more sources

Exposome in human health: Utopia or wonderland?

The Innovation, 2021
Summary: The current human exposome primarily emphasizes the total environmental exposure during an entire life. The characteristics of “lifelong” and “all environmental factors” make it very challenging to bring the exposomic study into real-life ...
Mingliang Fang, Ligang Hu, Da Chen, Yuming Guo, Jianmeng Liu, Changxin Lan, Jicheng Gong, Bin Wang   +7 more
doaj   +1 more source

PubChemLite for Exposomics (1 Jan 2021) + predicted CCS from CCSbase [PDF]

, 2021
PubChemLite is a subset of PubChem (https://pubchem.ncbi.nlm.nih.gov/) selected from major categories of the Table of Contents page at the PubChem Classification Browser (https://pubchem.ncbi.nlm.nih.gov/classification/#hid=72).
LCSB-ECI, Schymanski, Emma, Kondic, Todor, Zhang, Jeff, Thiessen, Paul, CCSbase Team, Xu, Libin, PubChem Team, Bolton, Evan, Ross, David H., Krinsky, Ally   +10 more
core   +1 more source

Assessing the Potential of Untargeted SWATH Mass Spectrometry-Based Metabolomics to Differentiate Closely Related Exposures in Observational Studies

Metabolites, 2022
Mass spectrometry (MS) is increasingly used in clinical studies to obtain molecular evidence of chemical exposures, such as tobacco smoke, alcohol, and drugs.
Frank Klont, Piotr Sosnowski, Daan Kremer, Tim J. Knobbe, Ron Bonner, Hans Blokzijl, Rinse K. Weersma, Stephan J. L. Bakker, TransplantLines Investigators, Eelko Hak, Daan J. Touw, Gérard Hopfgartner   +11 more
doaj   +1 more source