Replacement Strategies for Animal Studies in Inhalation Testing
Sci, 2021 Animal testing is mandatory in drug testing and is the gold standard for toxicity and efficacy evaluations. This situation is expected to change in the future as the 3Rs principle, which stands for the replacement, reduction, and refinement of the use of
Eleonore Fröhlich
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Integration of the PubAnnotation ecosystem in the development of a web-based search tool for alternative methods [PDF]
Genomics & Informatics, 2020 Finding publications that propose alternative methods to animal experiments is an important but time-consuming task since researchers need to perform various queries to literature databases and screen many articles to assess two important aspects: the ...
Mariana Neves
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In Vitro Antimicrobial Activities of Organic Acids and Their Derivatives on Several Species of Gram-Negative and Gram-Positive Bacteria. [PDF]
, 2019 The objective of this study was to determine the in vitro antimicrobial activity of several organic acids and their derivatives against Gram-positive (G+) and Gram-negative (G-) bacteria.
Atwill, Edward Robert +8 more
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Author Guide for Addressing Animal Methods Bias in Publishing
Advanced Science, 2023 There is growing recognition that animal methods bias, a preference for animal‐based methods where they are not necessary or where nonanimal‐based methods may already be suitable, can impact the likelihood or timeliness of a manuscript being accepted for
Catharine E. Krebs +8 more
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Predicting toxicity of chemicals: software beats animal testing
EFSA Journal, 2019 We created earlier a large machine‐readable database of 10,000 chemicals and 800,000 associated studies by natural language processing of the public parts of Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) registrations until
Thomas Hartung
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RE-Place: A Unique Project Collecting Expertise on New Approach Methodologies
Frontiers in Pharmacology, 2022 By applying “New Approach Methodologies (NAMs)” based on innovative technologies such as computer modeling, high throughput testing, omics, and sophisticated cell cultures, the use of experimental animals in the life sciences can be reduced or sometimes ...
Mieke Van Mulders +5 more
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Alternatives to animal testing: A review
Saudi Pharmaceutical Journal, 2015 The number of animals used in research has increased with the advancement of research and development in medical technology. Every year, millions of experimental animals are used all over the world. The pain, distress and death experienced by the animals during scientific experiments have been a debating issue for a long time. Besides the major concern
Doke, Sonali K., Dhawale, Shashikant C.
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Learning about a Moving Target in Resource Management: Optimal Bayesian Disease Control [PDF]
, 2017 Resource managers must often make difficult choices in the face of imperfectly observed and dynamically changing systems (e.g., livestock, fisheries, water, and invasive species).
Fackler, Paul L +2 more
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Vegetarians versus Vegans [PDF]
, 2020 There is a gap in literature related to studies that explicitly compare vegetarians to vegans, as existing studies typically group these diets together and examine carnivorous and omnivorous diets in order to identify similarities and differences.
Kaplan, Hannah
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Brain organoids and organoid intelligence from ethical, legal, and social points of view
Frontiers in Artificial IntelligenceHuman brain organoids, aka cerebral organoids or earlier “mini-brains”, are 3D cellular models that recapitulate aspects of the developing human brain.
Thomas Hartung +3 more
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