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Animal Testing Alternatives: Online Resources

open access: yesIssues in Science and Technology Librarianship, 2000
This article focuses on bibliographic databases and web sites that provide information on the scientific aspects of animal testing alternatives and not on the pros and cons of animal rights.
Elizabeth Choinski
doaj   +2 more sources

Alternatives to Animal Testing [PDF]

open access: yesJournal of Toxicology: Cutaneous and Ocular Toxicology, 2019
Animal experimentation has long been a controversial issue with impassioned arguments on both sides of the debate. Increasingly it has become more expedient and feasible to develop new methods that avoid the use of animals. There is agreement on both sides that reduction and refinement of experiments on animals should be an important goal for the ...
  +6 more sources

An Overview of Tissue Engineering as an Alternative for Toxicity Assessment [PDF]

open access: yes, 2016
Tissue engineering is a multidisciplinary field that combines aspects of biology, material sciences, engineering and medicine - the ultimate goal being able to fabricate replacement tissues and/or organs for an ageing population.
Chau, David Y.S., Garrod, Mathew
core   +2 more sources

Organotypic Models to Study Human Glioblastoma: Studying the Beast in Its Ecosystem

open access: yesiScience, 2020
Summary: Glioblastoma is a very aggressive primary brain tumor in adults, with very low survival rates and no curative treatments. The high failure rate of drug development for this cancer is linked to the high-cost, time-consuming, and inefficient ...
David Pamies   +2 more
doaj   +1 more source

Microglia Increase Inflammatory Responses in iPSC-Derived Human BrainSpheres

open access: yesFrontiers in Microbiology, 2018
Human induced pluripotent stem cells (iPSCs), together with 21st century cell culture methods, have the potential to better model human physiology with applications in toxicology, disease modeling, and the study of host-pathogen interactions.
Celina Monteiro Abreu   +9 more
doaj   +1 more source

Does low-energy sweetener consumption affect energy intake and body weight? A systematic review, including meta-analyses, of the evidence from human and animal studies [PDF]

open access: yes, 2015
By reducing energy density, low-energy sweeteners (LES) might be expected to reduce energy intake (EI) and body weight (BW). To assess the totality of the evidence testing the null hypothesis that LES exposure (versus sugars or unsweetened alternatives ...
de Graaf, C   +10 more
core   +5 more sources

Biomimetic heart platforms for drug development [PDF]

open access: yesOrganoid, 2022
New drug development is currently very expensive and time-consuming. In addition, some drugs that are approved after animal and clinical trials have their approval revoked because of adverse effects.
Sungwoo Cho, Sungho Ko
doaj   +1 more source

Antimicrobials in animal agriculture: Parables and policy [PDF]

open access: yes, 2015
In addition to the scientific, economic, regulatory and other policy factors that impact on antimicrobial decision-making in different jurisdictions around the world, there exist ethical, social and cultural bases for the contemporary use of these ...
Aarestrup   +43 more
core   +1 more source

Female and male Wistar rats (Rattus norvegicus) discriminate diets according to energetic quantity [PDF]

open access: yes, 2020
The food choice of animals is influenced by several factors including the quantity and nutrients available. It is not known, however, whether faced with alternatives that present the same amount of food, with similar flavor and obtained with the same ...
Aragon, Davi Casadele   +4 more
core  

Improving supplementary feeding in species conservation [PDF]

open access: yes, 2014
Supplementary feeding is often a knee-jerk reaction to population declines, and its application is not critically evaluated, leading to polarized views among managers on its usefulness. Here, we advocate a more strategic approach to supplementary feeding
Canessa, Stefano   +3 more
core   +1 more source

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