Results 51 to 60 of about 3,673,245 (381)
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac+3 more
wiley +1 more source
Zoo-sociocosmología qom: seres humanos, animales y sus relaciones en el Gran Chaco
Al margen de la zoologia academica existen otros sistemas de acuerdo a los que se organizan, clasifican, piensan y se establecen relaciones con los animales.
Celeste Medrano
semanticscholar +1 more source
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi+3 more
wiley +1 more source
Dans un article recent, Paul R. Ehrlich et Robert M. Pringle proposaient des mesures d’urgence pour endiguer l’erosion de la biodiversite a travers le monde, parmi lesquelles « un changement des attitudes humaines envers la nature » [2008 : 11 583]. Tandis que l’essentiel de leur programme s’adressait evidemment aux gouvernants, cette proposition s ...
openaire +2 more sources
Dans un contexte de demande croissante en proteines animales, l’elevage de precision et la selection animale doivent viser a accroitre la competitivite des systemes de production et a reduire leur impact environnemental.
F. Phocas+7 more
semanticscholar +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source