Results 41 to 50 of about 165,689 (258)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Safety Assessment of the CP4 EPSPS and NPTII Proteins in Eucalyptus

GM Crops & Food, 2023
Glyphosate herbicide treatment is essential to sustainable Eucalyptus plantation management in Brazil. Eucalyptus is highly sensitive to glyphosate, and Suzano/FuturaGene has genetically modified eucalyptus to tolerate glyphosate, with the aim of both ...
Dror Avisar, Shelly Azulay, Lorena Bombonato, Denise Carvalho, Heitor Dallapicolla, Carla de Souza, Anselmo dos Santos, Tatiane Dias, Maria Paula Galan, Milton Galvao, José Mateus Gonsalves, Esteban Gonzales, Rodrigo Graça, Sivan Livne, Reginaldo Mafia, Alexandre Manoeli, Mike May, Thaís Regina Drezza Menezes, Ana Cristina Pinheiro, Antonio Porto, Carolina Rocha, Ariane Schafer, Barry Schafer, Edival Zauza, William Silva   +24 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Acceptance of beef obtained through genetic modification and cloning in university students and working adults in southern Chile

Revista de la Facultad de Ciencias Agrarias, 2017
In order to compare the acceptance of beef obtained from a conventionally bred, cloned or genetically modified (GM) animal by working adults and university students, and to identify consumer segments in both subsamples, a survey of 400 people in ...
Berta Schnettler, Carlos Velásquez, Germán Lobos, Ligia Orellana, José Sepúlveda, Natalia Salinas-Oñate, Cristian Adasme-Berríos, Klaus G. Grunert   +7 more
doaj  

Transgenic Rabbit Models: Now and the Future

Applied Sciences, 2020
Transgenic rabbits have contributed to the progress of biomedical science as human disease models because of their unique features, such as the lipid metabolism system similar to humans and medium body size that facilitates handling and experimental ...
Fumikazu Matsuhisa, Shuji Kitajima, Kazutoshi Nishijima, Toshiaki Akiyoshi, Masatoshi Morimoto, Jianglin Fan   +5 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Monitoring of plant raw materials and feed for animal in 2020 for the presence of GM-ingredients

Науковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Ґжицького: Серія Ветеринарні науки, 2021
The creation and the use of genetically modified products has become a tendency in the development of agricultural and food technologies. The area of agricultural land under genetically modified plants is constantly growing.
G. V. Kushnir
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source