Results 141 to 150 of about 8,349,205 (432)

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Optimal Strouhal number for swimming animals [PDF]

, 2011
To evaluate the swimming performances of aquatic animals, an important dimensionless quantity is the Strouhal number, St = fA/U, with f the tail-beat frequency, A the peak-to-peak tail amplitude, and U the swimming velocity.
Abramowitz, Anderson, Anderson, Archer, Bainbridge, Bainbridge, Barrett, Blake, Blickhan, Borazjani, Brett, Bénard, Candelier, Cheng, Christophe Eloy, D'Août, D'Août, Dewar, Dickson, Doaré, Donley, Dowis, Ellerby, Fish, Fish, Fish, Gillis, Gillis, Gray, Hess, Horner, Huerre, Hunter, Jayne, Jordan, Kayan, Kern, Kojeszewski, Koochesfahani, Lauder, Liao, Lighthill, Lighthill, Long, Long, Long, Lowe, McMillen, Müller, Müller, Müller, Nauen, Parrish, Pier, Rayleigh, Read, Rinaldi, Rohr, Schouveiler, Schultz, Seebacher, Sfakiotakis, Shirgaonkar, Strouhal, Taylor, Triantafyllou, Triantafyllou, Triantafyllou, Tytell, Videler, Videler, Videler, Videler, Wardle, Wassersug, Webb, Webb, Webb, Webb, Webb, Webb, Webb, Webb, Webber, Wu, Wu, Yuen   +86 more
core   +3 more sources

Disconnexion syndromes in animals and man. I.

Brain : a journal of neurology, 1965
As I have pointed out earlier, when I met Oliver Zangwill in 1961 at a meeting on dyslexia in Baltimore, he listened patiently to the exposition of my ideas on the significance of the cortico-cortical connections for the higher functions.
N. Geschwind
semanticscholar   +1 more source

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

FEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze, Stéphane Canaan, Alexandre Gouzy, Pierre Santucci   +3 more
wiley   +1 more source

Exposure system for animals Patent [PDF]

, 1968
System for continuous monitoring of exhalations, weighing, and cage cleaning for animal exposed to controlled atmosphere for toxic ...
Quattrone, P. D., Staley, R. W.
core   +1 more source

Unconventional mRNA processing and degradation pathways for the polycistronic yrzI (spyTA) mRNA in Bacillus subtilis

FEBS Letters, EarlyView.
The S1025 peptide is the major antidote to the YrzI toxin, which we renamed here as SpyT (Small Peptide YrzI Toxin) and SpyA (Small Peptide YrzI Antitoxin) (1). Degradation of the toxin–antitoxin spyTA mRNA, either by a translation‐dependent cleavage by the endoribonuclease Rae1 (2) or by direct attack by 3′‐exoribonucleases (3), also contributes to ...
Laetitia Gilet, Magali Leroy, Alexandre Maes, Ciarán Condon, Frédérique Braun   +4 more
wiley   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

FEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma, Jennifer R. Deuis, Xinying Jia, Theo Crawford, Sassan Rahnama, Eivind A. B. Undheim, Irina Vetter, Yanni K. ‐Y. Chin, Mehdi Mobli   +8 more
wiley   +1 more source

Animated $λ$-rings and Frobenius lifts [PDF]

arXiv
In this note, we study an integral analogue of animated $\delta$-rings: Animated $\lambda$-rings. We define animated $\lambda$-rings in terms of animated rings equipped with a structure of coherently compatible Frobenius lifts and show that the resulting $\infty$-category is obtained from animating the classical notion of a $\lambda$-ring.
arxiv  

Graphical Perception in Animated Bar Charts [PDF]

arXiv, 2016
Interactive visual applications create animations that encode changes in the data. For example, cross-filtering dynamically updates linked visualizations based on the user's continuous brushing actions. The animated effects resulting from these interactions depends both on how interaction (e.g., brushing speed) controls properties of the animation such
arxiv  

I. On the classification of the fossil animals commonly named Dinosauria [PDF]

, 1888
H. G. Seeley
openalex   +1 more source