Results 61 to 70 of about 1,775,336 (273)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

Novel nanomaterials for anion recognition [PDF]

open access: yes
Abundant anions in the body, like chloride and sulphate, are the target of many studies involving anion recognition. In the past 30 years, different kinds of anion receptors have been intensively studied including small molecule receptors with the aim of
Castilla, Ana Maria   +2 more
core   +4 more sources

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

open access: yesFEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan   +2 more
wiley   +1 more source

Communicating Recognition & Rewards experiences: Tips and tricks

open access: yes
These guidelines support communications and marketing employees in the preparation and execution stages of creating a story about someone’s experiences with Recognition & Rewards (R&R) principles and themes.
Recognition & Rewards
core   +2 more sources

The development of imidazolium-based anion recognition functional materials and perfluorinated anion removal from water [PDF]

open access: yes
Imidazolium quaternary salts are a versatile class of cationic building blocks that allow for anion recognition chemistry, ionic liquids, and N-heterocyclic carbenes (NHCs), making them suitable motifs for designing systems in a broad range of ...
Ahmed, Mehroz
core   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

open access: yesFEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn   +2 more
wiley   +1 more source

Novel nanomaterials for anion-recognition [PDF]

open access: yes, 2022
Abundant anions in the body, like chloride and sulphate, are the target of many studies involving anion recognition. In the past 30 years, different kinds of anion receptors have been intensively studied including small molecule receptors with the aim of
Castilla, Ana Maria, Oder, Oriane
core   +2 more sources

Squaramide—Naphthalimide Conjugates as “Turn-On” Fluorescent Sensors for Bromide Through an Aggregation-Disaggregation Approach

open access: yesFrontiers in Chemistry, 2019
The syntheses of two new squaramide-naphthalimide conjugates (SQ1 and SQ2) are reported where both compounds have been shown to act as selective fluorescence “turn on” probes for bromide in aqueous DMSO solution through a disaggregation induced response.
Lokesh K. Kumawat   +9 more
doaj   +1 more source

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