Results 1 to 10 of about 80,553 (266)

Identification and characterization of the three members of the CLC family of anion transport proteins in Trypanosoma brucei. [PDF]

PLoS ONE, 2017
CLC type anion transport proteins are homo-dimeric or hetero-dimeric with an integrated transport function in each subunit. We have identified and partially characterized three members of this family named TbVCL1, TbVCL2 and TbVCL3 in Trypanosoma brucei.
Michael E Steinmann, Remo S Schmidt, Juan P Macêdo, Christina Kunz Renggli, Peter Bütikofer, Doris Rentsch, Pascal Mäser, Erwin Sigel   +7 more
doaj   +2 more sources

Picrotoxin Delineates Different Transport Configurations for Malate and γ Aminobutyric Acid through TaALMT1

Biology, 2022
Plant-derived pharmacological agents have been used extensively to dissect the structure–function relationships of mammalian GABA receptors and ion channels. Picrotoxin is a non-competitive antagonist of mammalian GABAA receptors.
Sunita A. Ramesh, Yu Long, Abolfazl Dashtbani-Roozbehani, Matthew Gilliham, Melissa H. Brown, Stephen D. Tyerman   +5 more
doaj   +1 more source

Preference of Proteomonas sulcata anion channelrhodopsin for NO3 − revealed using a pH electrode method

Scientific Reports, 2021
Ion channel proteins are physiologically important molecules in living organisms. Their molecular functions have been investigated using electrophysiological methods, which enable quantitative, precise and advanced measurements and thus require complex ...
Chihiro Kikuchi, Hina Kurane, Takuma Watanabe, Makoto Demura, Takashi Kikukawa, Takashi Tsukamoto   +5 more
doaj   +1 more source

Light-Modulated Cationic and Anionic Transport Across Protein Biopolymers [PDF]

Angewandte Chemie International Edition, 2021
Abstract Light is a convenient source of energy and the heart of light‐harvesting natural systems and devices. Here, we show light‐modulation of both the chemical nature and ionic charge carrier concentration within a protein‐based biopolymer that was covalently functionalized with photoacids or photobases.
Alex Burnstine‐Townley, Somen Mondal, Yuval Agam, Ramesh Nandi, Nadav Amdursky   +4 more
openaire   +2 more sources

Anion Transport Using Core Functionalized Hyperbranched Polymers and Evidence of a Dense Packed Limit Based on Molecular Weight

Molecules, 2021
Being able to bind, select, and transport species is central to a number of fields, including medicine, materials, and environmental science. In particular, recognizing a specific species from one phase and transporting it across, or into another phase ...
Sozan Najib Abdullah, Georgia Mann, Lance J. Twyman   +2 more
doaj   +1 more source

Structural and functional properties of the transporter SLC26A6 reveal mechanism of coupled anion exchange

eLife, 2023
Members of the SLC26 family constitute a conserved class of anion transport proteins, which encompasses uncoupled transporters with channel-like properties, coupled exchangers and motor proteins.
David N Tippett, Colum Breen, Stephen J Butler, Marta Sawicka, Raimund Dutzler   +4 more
doaj   +1 more source

Mutations conferring SO4 2− pumping ability on the cyanobacterial anion pump rhodopsin and the resultant unique features of the mutant

Scientific Reports, 2022
Membrane transport proteins can be divided into two types: those that bind substrates in a resting state and those that do not. In this study, we demonstrate that these types can be converted by mutations through a study of two cyanobacterial anion ...
Yuhei Doi, Jo Watanabe, Ryota Nii, Takashi Tsukamoto, Makoto Demura, Yuki Sudo, Takashi Kikukawa   +6 more
doaj   +1 more source

A Balance between Transmembrane-Mediated ER/Golgi Retention and Forward Trafficking Signals in Glycophorin-Anion Exchanger-1 Interaction

Cells, 2022
Anion exchanger-1 (AE1) is the main erythroid Cl−/HCO3− transporter that supports CO2 transport. Glycophorin A (GPA), a component of the AE1 complexes, facilitates AE1 expression and anion transport, but Glycophorin B (GPB) does not.
Kate Hsu, Ting-Ying Lee, Jian-Yi Lin, Pin-Lung Chen   +3 more
doaj   +1 more source

Organization and Dynamics of the Red Blood Cell Band 3 Anion Exchanger SLC4A1: Insights From Molecular Dynamics Simulations

Frontiers in Physiology, 2022
Molecular dynamics (MD) simulations have provided new insights into the organization and dynamics of the red blood cell Band 3 anion exchanger (AE1, SLC4A1).
Antreas C. Kalli, Reinhart A. F. Reithmeier   +1 more
doaj   +1 more source

Organic Anion Transporting Polypeptide 3A1 (OATP3A1)-Gated Bio-Orthogonal Labeling of Intracellular Proteins

Molecules, 2023
Organic anion transporting polypeptides (OATPs) were found to readily deliver membrane impermeable, tetrazine bearing fluorescent probes into cells. This feature was explored in OATP3A1 conditioned bio-orthogonal labeling schemes of various intracellular
Krisztina Németh, Zsófia László, Adrienn Biró, Ágnes Szatmári, Gergely B. Cserép, György Várady, Éva Bakos, Csilla Özvegy-Laczka, Péter Kele   +8 more
doaj   +1 more source