Results 21 to 30 of about 3,774,880 (304)
Molecules, 2023 Organic anion transporting polypeptides (OATPs) were found to readily deliver membrane impermeable, tetrazine bearing fluorescent probes into cells. This feature was explored in OATP3A1 conditioned bio-orthogonal labeling schemes of various intracellular
Krisztina Németh +8 more
doaj +1 more source
Light-Modulated Cationic and Anionic Transport Across Protein Biopolymers [PDF]
Angewandte Chemie International Edition, 2021 Light is a convenient source of energy and the heart of light-harvesting natural systems and devices. Here, we show light-modulation of both the chemical nature and ionic charge carrier concentration within a protein-based biopolymer that was covalently functionalized with photoacids or photobases.
Alex Burnstine‐Townley +4 more
openaire +2 more sources
Novel (sulfated) thyroid hormone transporters in the solute carrier 22 family
European Thyroid Journal, 2023 Objective: Thyroid hormone (TH) transport represents a critical first step in governing intracellular TH regulation. It is still unknown whether the full repertoire of TH transporters has been identified.
Zhongli Chen +11 more
doaj +1 more source
Identification of steroid sulfate transport processes in the human mammary gland [PDF]
, 2003 Circulating hormones and local biotransformation of steroid precursors are both sources of estrogen in human mammary tissue. Estrone-3-sulfate (E(1)S) is an important estrogenic form in premenopausal women, and dehydroepiandrosterone sulfate (DHEAS ...
Pizzagalli, F. +5 more
core +1 more source
Characterization of an organic anion-transporting polypeptide (OATP-B) in human placenta [PDF]
, 2002 Organic anion-transporting polypeptides (OATPs) are a family of multispecific carriers that mediate the sodium-independent transport of steroid hormone and conjugates, drugs, and numerous anionic endogenous substrates.
Stallmach, T. +4 more
core +1 more source
Plant Direct, 2021 Polar auxin transport through plant tissue strictly requires polarly localized PIN proteins and uniformly distributed ABCB proteins. A functional synergy between the two types of membrane protein where their localizations overlap may create the degree of
Stephen D. Deslauriers +1 more
doaj +1 more source
mBio, 2013 Wzx flippases are crucial for bacterial cell surface polysaccharide assembly as they transport undecaprenyl pyrophosphate-linked sugar repeat units from the cytoplasmic to the periplasmic leaflets of the inner membrane (IM) for final assembly.
Salim T. Islam +6 more
doaj +1 more source
The Human Organic Anion Transport Protein SLC21A6 Is Not Sufficient for Bilirubin Transport [PDF]
Journal of Biological Chemistry, 2003 A recent study (Cui, Y., Konig, J., Leier, I., Buchholz, U., and Keppler, D. (2001) J. Biol. Chem. 276, 9626-9630) suggests that human OATP2 (SLC21A6), also known as OATP-C and LST1, mediates hepatic bilirubin transport. Because of methodologic concerns, this study was designed to examine this issue using a bilirubin transport assay that was validated ...
Pijun, Wang +3 more
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Transport of proteins into mitochondria [PDF]
, 1985 Translocational intermediates of precursor proteins of ATPase F1β subunit and cytochrome c1 across mitochondrial membranes were analyzed using two different approaches, transport at low temperature and transport after binding of precursor proteins to ...
Schleyer, Manfred, Neupert, Walter
core +1 more source
Urinary organic anion transporter protein profiles in AKI [PDF]
Nephrology Dialysis Transplantation, 2011 Organic anion transporters (OATs) are located on either the basolateral or the apical membrane of the proximal tubule cell and mediate the absorption and secretion of various drugs and endogenous metabolites. It has been shown that cellular damage in acute kidney injury (AKI) involves three forms of injury: sublethal damage resulting in loss of cell ...
Margarita, Kunin +3 more
openaire +2 more sources