Results 21 to 30 of about 80,553 (266)
Bioinformatic characterization of the Anoctamin Superfamily of Ca2+-activated ion channels and lipid scramblases. [PDF]
PLoS ONE, 2018 Our laboratory has developed bioinformatic strategies for identifying distant phylogenetic relationships and characterizing families and superfamilies of transport proteins.
Arturo Medrano-Soto +5 more
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Anion Transport by Proteins: Protein Motifs Involved in Anion Binding
, 2022 Various cellular processes require the participation of specific anions, including Cl-, F-, I-, HCO3- and CO32-. However, their ionic charges impede their permeation across the hydrophobic lipid bilayers of the cells. Cell membranes thus contain specific macromolecular transport proteins, ion channels and transporters, to facilitate and control the ...
openaire +2 more sources
Membranes, 2020 Transmembrane transport of monocarboxylates is conferred by structurally diverse membrane proteins. Here, we describe the pH dependence of lactic acid/lactate facilitation of an aquaporin (AQP9), a monocarboxylate transporter (MCT1, SLC16A1), and a ...
Annika Bader, Eric Beitz
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The Role of Uptake and Efflux Transporters in the Disposition of Glucuronide and Sulfate Conjugates
Frontiers in Pharmacology, 2022 Glucuronidation and sulfation are the most typical phase II metabolic reactions of drugs. The resulting glucuronide and sulfate conjugates are generally considered inactive and safe.
Erkka Järvinen +6 more
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A Lipid Bilayer Formed on a Hydrogel Bead for Single Ion Channel Recordings
Micromachines, 2020 Ion channel proteins play important roles in various cell functions, making them attractive drug targets. Artificial lipid bilayer recording is a technique used to measure the ion transport activities of channel proteins with high sensitivity and ...
Minako Hirano +6 more
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Expression of calcification‐related ion transporters during blue mussel larval development
Ecology and Evolution, 2019 The physiological processes driving the rapid rates of calcification in larval bivalves are poorly understood. Here, we use a calcification substrate‐limited approach (low dissolved inorganic carbon, CT) and mRNA sequencing to identify proteins involved ...
Kirti Ramesh +4 more
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Enantioselective Drug Recognition by Drug Transporters
Molecules, 2018 Drug transporters mediate the absorption, tissue distribution, and excretion of drugs. The cDNAs of P-glycoprotein, multidrug resistance proteins (MRPs/ABCC), breast cancer resistance protein (BCRP/ABCG2), peptide transporters (PEPTs/SLC15), proton ...
Yuichi Uwai
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Biosynthesis of the erythrocyte anion transport protein.
Journal of Biological Chemistry, 1981 The biosynthesis of the erythrocyte anion transport protein (Band III) was studied in erythroid precursor cells obtained from the spleens of anemic mice. Newly synthesized Band III was inserted during or immediately after translation into rough endoplasmic reticulum membranes.
W A, Braell, H F, Lodish
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Insights into the Mechanisms Underlying Boron Homeostasis in Plants
Frontiers in Plant Science, 2017 Boron is an essential element for plants but is toxic in excess. Therefore, plants must adapt to both limiting and excess boron conditions for normal growth.
Akira Yoshinari, Junpei Takano
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Multiple ALMT subunits combine to form functional anion channels: A case study for rice ALMT7
Frontiers in Plant Science, 2022 The Aluminum Activated Malate Transporter (ALMT) family members are anion channels that play important roles in organic acid transport, stress resistance, growth, development, fertilization and GABA responses. The rice malate permeable OsALMT7 influences
Hui Zhou +4 more
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