Results 11 to 20 of about 80,553 (266)
Novel (sulfated) thyroid hormone transporters in the solute carrier 22 family
European Thyroid Journal, 2023 Objective: Thyroid hormone (TH) transport represents a critical first step in governing intracellular TH regulation. It is still unknown whether the full repertoire of TH transporters has been identified.
Zhongli Chen +11 more
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The Human Organic Anion Transport Protein SLC21A6 Is Not Sufficient for Bilirubin Transport [PDF]
Journal of Biological Chemistry, 2003 A recent study (Cui, Y., Konig, J., Leier, I., Buchholz, U., and Keppler, D. (2001) J. Biol. Chem. 276, 9626-9630) suggests that human OATP2 (SLC21A6), also known as OATP-C and LST1, mediates hepatic bilirubin transport. Because of methodologic concerns, this study was designed to examine this issue using a bilirubin transport assay that was validated ...
Pijun, Wang +3 more
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Urinary organic anion transporter protein profiles in AKI [PDF]
Nephrology Dialysis Transplantation, 2011 Organic anion transporters (OATs) are located on either the basolateral or the apical membrane of the proximal tubule cell and mediate the absorption and secretion of various drugs and endogenous metabolites. It has been shown that cellular damage in acute kidney injury (AKI) involves three forms of injury: sublethal damage resulting in loss of cell ...
Margarita, Kunin +3 more
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Monomeric erythrocyte band 3 protein transports anions. [PDF]
Proceedings of the National Academy of Sciences, 1991 The anion transport system of the human erythrocyte membrane was reconstituted in egg phosphatidylcholine membranes by using either the unmodified transport protein, band 3, or covalently crosslinked band 3 dimers. Unilamellar vesicles of a diameter of 32 +/- 3 nm were then isolated from the sample by passage through a French press and subsequent gel ...
Lindenthal, S., Schubert, D.
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Plant Direct, 2021 Polar auxin transport through plant tissue strictly requires polarly localized PIN proteins and uniformly distributed ABCB proteins. A functional synergy between the two types of membrane protein where their localizations overlap may create the degree of
Stephen D. Deslauriers +1 more
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mBio, 2013 Wzx flippases are crucial for bacterial cell surface polysaccharide assembly as they transport undecaprenyl pyrophosphate-linked sugar repeat units from the cytoplasmic to the periplasmic leaflets of the inner membrane (IM) for final assembly.
Salim T. Islam +6 more
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Anion transport by the cochlear motor protein prestin
The Journal of Physiology, 2011 Non‐technical summary Cochlear inner hair cells transform acoustic signals into electric signals. Another type of hair cells, outer hair cells, actively amplifies sensory signals and thus contributes to the exquisite sensitivity of the human auditory system.
Michael, Schänzler, Christoph, Fahlke
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Engineered Pendrin Protein, an Anion Transporter and Molecular Motor [PDF]
Journal of Biological Chemistry, 2011 Pendrin and prestin both belong to a distinct anion transporter family called solute carrier protein 26A, or SLC26A. Pendrin (SLC26A4) is a chloride-iodide transporter that is found at the luminal membrane of follicular cells in the thyroid gland as well as in the endolymphatic duct and sac of the inner ear, whereas prestin (SLC26A5) is expressed in ...
Jie, Tang +4 more
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Prediction of membrane transport proteins and their substrate specificities using primary sequence information. [PDF]
PLoS ONE, 2014 Membrane transport proteins (transporters) move hydrophilic substrates across hydrophobic membranes and play vital roles in most cellular functions. Transporters represent a diverse group of proteins that differ in topology, energy coupling mechanism ...
Nitish K Mishra +2 more
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Effect of a bound anion on the structure and dynamics of halorhodopsin from Natronomonas pharaonis
Structural Dynamics, 2019 Active ion transport across membranes is vital to maintaining the electrochemical gradients of ions in cells and is mediated by transmembrane proteins. Halorhodopsin (HR) functions as a light-driven inward pump for chloride ions. The protein contains all-
Misao Mizuno +3 more
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