Halide-selective, proton-coupled anion transport by phenylthiosemicarbazones [PDF]
, 2021 Phenylthiosemicarbazones (PTSCs) are proton-coupled anion transporters with pH-switchable behaviour known to be regulated by an imine protonation equilibrium.
Vai-Vai Tiffany, Chang +6 more
core +2 more sources
Structural basis for the reaction cycle of DASS dicarboxylate transporters
eLife, 2020 Citrate, α-ketoglutarate and succinate are TCA cycle intermediates that also play essential roles in metabolic signaling and cellular regulation. These di- and tricarboxylates are imported into the cell by the divalent anion sodium symporter (DASS ...
David B Sauer +8 more
doaj +1 more source
Biosynthesis of the erythrocyte anion transport protein.
Journal of Biological Chemistry, 1981 The biosynthesis of the erythrocyte anion transport protein (Band III) was studied in erythroid precursor cells obtained from the spleens of anemic mice. Newly synthesized Band III was inserted during or immediately after translation into rough endoplasmic reticulum membranes.
W A, Braell, H F, Lodish
openaire +2 more sources
In vitro transport of methotrexate by Drosophila Multidrug Resistance-associated Protein. [PDF]
PLoS ONE, 2018 Methotrexate (MTX) is a widely used chemotherapeutic agent, immune suppressant and antimalarial drug. It is a substrate of several human ABC proteins that confer multidrug resistance to cancer cells and determine compartmentalization of a wide range of ...
Agnes Karasik +2 more
doaj +1 more source
Protocol: optimised electrophyiological analysis of intact guard cells from arabidopsis [PDF]
, 2012 Genetic resources available for Arabidopsis thaliana make this species particularly attractive as a model for molecular genetic studies of guard cell homeostasis, transport and signalling, but this facility is not matched by accessible tools for ...
Adrian Hills +19 more
core +1 more source
Transmembrane Anion Transport Promoted by Thioamides [PDF]
, 2021 Thioamide groups represent useful hydrogen-bonding motifs for the development of active transmembrane anion transporters. Using a 1,8-dithioamidocarbazole scaffold the superior performance of thioamides compared with the parent amides has been ...
roberto, quesada +3 more
core +1 more source
Molecular cloning and characterization of the chloride channel gene family in trifoliate orange
Biologia Plantarum, 2015 Chloride channels (CLCs) play pivotal roles in plant development and anion transport. However, little research has been conducted about the CLC in fruit-bearing plants.
Q. J. Wei +4 more
doaj +1 more source
Hepatocanalicular organic-anion transport is regulated by protein kinase C [PDF]
Biochemical Journal, 1991 In order to investigate the regulation of canalicular organic-anion transport, we used a hepatocyte transport assay in which canalicular secretion of a model organic anion, dinitrophenyl-glutathione (GS-DNP), was measured in the presence of stimulators and inhibitors of the Ca2+/protein kinase C (PKC) second-messenger system and of the cyclic AMP (cAMP)
Roelofsen, H. +3 more
openaire +3 more sources
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Motivated proteins: a web application for studying small three-dimensional protein motifs [PDF]
, 2009 <b>BACKGROUND:</b> Small loop-shaped motifs are common constituents of the three-dimensional structure of proteins. Typically they comprise between three and seven amino acid residues, and are defined by a combination of dihedral angles and ...
Milner-White, E.J. +5 more
core +1 more source