Results 151 to 160 of about 77,929 (279)

A Randomized, Placebo‐Controlled Trial of Hydroxychloroquine in Incomplete Lupus

open access: yesArthritis &Rheumatology, Volume 78, Issue 4, Page 870-879, April 2026.
Objective Patients with features of systemic lupus erythematosus (SLE) who do not fulfill classification criteria can be designated as incomplete lupus erythematosus (ILE). This condition includes individuals with a high risk of progression to SLE. Treatment of ILE may reduce symptoms, severity, and incidence of SLE.
Nancy J. Olsen   +14 more
wiley   +1 more source

Is there a relationship between endothelial nitric oxide synthase gene polymorphisms and ankylosing spondylitis?

open access: yesClinics, 2013
OBJECTIVE: Nitric oxide is produced by endothelial nitric oxide synthase, and its production can be influenced by polymorphisms of the endothelial nitric oxide synthase gene.
Ismail Sari   +9 more
doaj  

Serious Infections in Offspring Exposed to Tumor Necrosis Factor Inhibitors During Pregnancy: Comparison of Timing During Pregnancy and Placental Transfer Ability

open access: yesArthritis &Rheumatology, Volume 78, Issue 4, Page 976-984, April 2026.
Objective We evaluated serious infection risk in offspring exposed to tumor necrosis factor inhibitors (TNFi) in utero, separated by TNFi timing and placental transfer ability. Methods Using MarketScan (2011–2021), we identified offspring born to mothers with chronic inflammatory diseases.
Leah K. Flatman   +6 more
wiley   +1 more source

Predicting Potential Treatment Targets for Fatigue in Chronic Fatigue Syndrome Using Thalamic Seeding

open access: yesBrain and Behavior, Volume 16, Issue 4, April 2026.
Bilateral thalamic seeding identified a candidate cortical target near PO7 in the left lateral occipital cortex. Its FC correlated with fatigue severity and exercise‐induced fatigue in CFS, suggesting an FC‐guided framework for future NIBS targeting fatigue symptoms.
Kang Wu   +7 more
wiley   +1 more source

Risk Factors and Comparative Safety of Anti‐PD‐1 Combination Therapies in Advanced Melanoma: A Nationwide Real‐World Cohort Study From China

open access: yesCancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Backgroud Different anti‐PD‐1 combination therapies are used to improve response rate and combat drug resistance for melanoma in the real world of China. While the reported safety data has remained scarce, especially for the controversial use of interferon.
Yuan Qiao   +21 more
wiley   +1 more source

Effects of Cedirogant on the Pharmacokinetics of Sensitive Cytochrome P450 Probe Substrates

open access: yesClinical Pharmacology in Drug Development, Volume 15, Issue 4, April 2026.
Abstract This study aimed to characterize the effects of cedirogant, an inverse agonist of retinoic acid–related orphan receptor gamma thymus (RORγt), on activities of cytochrome P450 (CYP) enzymes in healthy adults. Twenty study participants received a single oral dose of the modified Cooperstown 5+1 cocktail CYP probe drugs alone without cedirogant ...
Ronilda D'Cunha   +8 more
wiley   +1 more source

Case reports: Pulmonary destructive lesions caused by ankylosing spondylitis. [PDF]

open access: yesJ Clin Tuberc Other Mycobact Dis
Zhan S, Zhang H, Peng Q, Qin H, Zhang P.
europepmc   +1 more source

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action

open access: yesComprehensive Physiology, Volume 16, Issue 2, April 2026.
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu   +11 more
wiley   +1 more source

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