Results 151 to 160 of about 69,379 (288)

Protein tandem repeats that produce frameshifts can generate new structural states and functions

The FEBS Journal, Volume 293, Issue 3, Page 842-858, February 2026.
We explored an alternative protein structure landscape by analyzing amino acid sequences from frameshifted tandem repeats—regions prone to frameshifts. These frameshifts, especially in short repeats, lead to more drastic changes than in non‐repetitive regions, often altering structure, function, localization, and potentially contributing to disease ...
Zarifa Osmanli, Gudrun Aldrian, Jeremy Leclercq, Theo Falgarone, Santiago M. Gómez Bergna, Denis N. Prada Gori, Andrew V. Oleinikov, Ilham Shahmuradov, Andrey V. Kajava   +8 more
wiley   +1 more source

TRPM8 Regulates Mitochondrial Ca2+‐Dynamics, Temperature and Endoplasmic Reticulum‐Mitochondrial Contact Points in T Cell

Journal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.
ABSTRACT TRPM8 is a cold temperature‐sensitive and non‐selective Ca2+‐channel. Previously we have observed that TRPM8 is endogenously expressed and affects T cell activation process. Now, we report that TRPM8 regulates functions of mitochondria and ER, two important sub‐cellular compartments.
Tusar Kanta Acharya, Shamit Kumar, Tejas Pravin Rokade, Parnasree Mahapatra, Young Tae Chang, Chandan Goswami   +5 more
wiley   +1 more source

A T-lymphoma transmembrane glycoprotein (gp180) is linked to the cytoskeletal protein, fodrin. [PDF]

, 1985
A major mouse T-lymphoma surface glycoprotein (gp180) has been identified by labeling cells with 125I and [3H]glucosamine. After ligand-induced receptor patching and/or capping, the amount of gp 180 in the membrane-associated cytoskeleton fraction ...
Bourguignon, LY, Glenney, JR, Nagpal, ML, Suchard, SJ   +3 more
core  

Selection and Characterization of Her2 Binding-designed Ankyrin Repeat Proteins [PDF]

, 2006
Christian Zahnd, Frédéric Pecorari, Nadine Straumann, Emanuel Wyler, Andreas Plückthun   +4 more
openalex   +1 more source

Myopathy With Exercise‐Induced Intolerance due to Novel Biallelic Variants in OBSCN—A Clinical, Morphological and Molecular Analysis

Neuropathology and Applied Neurobiology, Volume 52, Issue 1, February 2026.
The phenotype of OBSCN variants consists of exercise intolerance ranging from myalgia and cramps to rhabdomyolysis. Symptoms are mainly induced by high‐intensity sports. Molecular analysis showing a deregulation of muscle processes associated with Ca2+ regulation, extrasarcolemmal integrity and autophagy emphasised the critical role of obscurin in ...
Heidrun H. Krämer‐Best, Marlen C. Reis, Andreas Hentschel, Michaela Weiß, Alexander Schaiter, Klaus‐Dieter Böhm, Andreas Roos, Dagmar Nolte, Anne Schänzer   +8 more
wiley   +1 more source

Expression of the ankyrin repeat domain 6 gene (Ankrd6) during mouse brain development [PDF]

, 2002
Fadel Tissir, Isabelle Bar, André M. Goffinet, Catherine Lambert de Rouvroit   +3 more
openalex   +1 more source

Mask, the Drosophila ankyrin repeat and KH domain-containing protein, affects microtubule stability [PDF]

, 2021
Daniel A. Martinez, Mingwei Zhu, Jessie J. Guidry, Niles Majeste, Hui Mao, Sarah T. Yanofsky, Xiaolin Tian, Chunlai Wu   +7 more
openalex   +1 more source

Transcriptional outputs and condensates – formation and function

New Phytologist, Volume 249, Issue 3, Page 1145-1154, February 2026.
Summary The dynamic spatiotemporal organization of macromolecules is key to the proper function of the cell, allowing the exquisite regulation of diverse processes from gene expression to enzymatic function. The formation of biomolecular condensates via phase separation (PS) acts as a general mechanism for selectively concentrating proteins, nucleic ...
Stephanie Hutin, Jiawei Li, Mark D. Tully, Xuelei Lai, Chloe Zubieta   +4 more
wiley   +1 more source

Regulation of perisomatic synapses from cholecystokinin basket interneurons through NrCAM and Ankyrin B

Current Research in Neurobiology
The perisomatic region of cortical pyramidal neurons (PNs) integrates local and long-range inputs and regulates firing. This domain receives GABAergic inputs from cholecystokinin (CCK)- and Parvalbumin (PV)-expressing basket cells (BCs) but how synaptic ...
Erik N. Oldre, Barrett D. Webb, Justin E. Sperringer, Patricia F. Maness   +3 more
doaj   +1 more source

ASAP1 (ArfGAP with SH3 domain, ankyrin repeat and PH domain 1)

, 2012
Hisataka Sabe, Yasuyuki Onodera, A Hashimoto, Shigeru Hashimoto   +3 more
openalex   +2 more sources