Results 131 to 140 of about 36,997 (223)
Abstract Background and Purpose Allergic contact dermatitis (ACD) is a frequent inflammatory skin disease with limited therapeutic options. While neuronal Transient Receptor Potential Ankyrin 1 (TRPA1) has been implicated in ACD, the role of keratinocyte TRPA1 remains unclear.
Areej Jaber +8 more
wiley +1 more source
Impaired AIS plasticity in ankyrin-G mutant mice alters cortical excitability and behavior. [PDF]
Li M +11 more
europepmc +1 more source
The G protein–coupled receptor (GPCR) superfamily consists of the most common targets of approved drugs. Targeting GPCRs offers appealing avenues for therapeutic development. Antibodies and their fragments, such as single‐domain antibodies (VHHs or nanobodies), have emerged as useful alternatives to small molecule pharmacophores as building blocks in ...
Shivani Sachdev, Ross W. Cheloha
wiley +1 more source
Molecular profiles of red blood cells across geographic, pathological, and age-related perspectives: translational insights. [PDF]
Almadhaani KY, Altaie AM, Hamoudi R.
europepmc +1 more source
ABSTRACT Context Placental calcium (Ca2+) transport is essential for foetal bone mineralisation and development, as well as for Ca2+ homoeostasis. Rare mutations in transient receptor potential vanilloid (TRPV) 6 of the infant cause insufficient maternal‐foetal Ca2+ transport through the placenta.
Teodora Grigore +6 more
wiley +1 more source
Oncolytic myxoma virus and engineering strategies for advanced cancer immunotherapy. [PDF]
Trujillo Yeriomenko AD +5 more
europepmc +1 more source
ABSTRACT Background Inherited platelet disorders (IPDs) are rare hematologic conditions encompassing a heterogeneous spectrum of quantitative and qualitative platelet defects, frequently associated with variable clinical phenotypes and comorbidities. Accurate diagnosis necessitates comprehensive genetic characterization, detailed clinical and bleeding ...
Silvia Ferrari +6 more
wiley +1 more source
14‐3‐3 proteins: Central hubs in plant development and stress adaptation
This review highlights recent advances elucidating the important roles of 14‐3‐3 proteins in regulating phytohormone networks, biotic and abiotic stress tolerance, growth‐defense trade‐offs, and evolutionary adaptations. Furthermore, it provides a forward‐looking perspective on 14‐3‐3 biology and the development of climate‐resilient smart crops under ...
Jiale Yuan +6 more
wiley +1 more source
Special Issue "Cellular and Molecular Progression of Cardiovascular Diseases". [PDF]
Borghini A, Rizza A, Tonacci A.
europepmc +1 more source

