Results 141 to 150 of about 36,997 (223)

Complex Contributions of Methylglyoxal to Pain, Axon Degeneration, and Diabetic Peripheral Neuropathy

Journal of Neurochemistry, Volume 170, Issue 8, August 2026.
This work reviews how the metabolic by‐product methylglyoxal may contribute to the development of diabetic peripheral neuropathy (DPN), a common complication of diabetes characterized by nerve damage and chronic pain in the extremities. In diabetes, methylglyoxal levels rise due to increased glucose metabolism and reduced detoxification capacity. While
Gentry Totta‐Griese, Douglas E. Wright
wiley   +1 more source

Non-superagonist CD28-based dual-signal T cell engager targeting. [PDF]

J Immunother Cancer
Chen T, Wang Y, Chen X, Li Y, Guo J, Liu F, Shao J, Yan J, Li M, Nie J, Sun Q, Liu Q, Liu B.   +12 more
europepmc   +1 more source

Schwann Cell TRPA1, a Proalgesic Ion Channel, Mediates Neuroinflammation and Fibromyalgia-Associated Behaviours in Mice. [PDF]

J Neurochem
Brum ES, Fialho MFP, de Araújo DSM, Landini L, Marini M, De Logu F, Nassini R, Oliveira SM.   +7 more
europepmc   +1 more source

Ankyrin Mutations in Hereditary Spherocytosis [PDF]

Acta Haematologica, 2019
openaire   +2 more sources

Physiological mechanisms and therapeutic targets in chronic cough

Physiological Reports, Volume 14, Issue 15, August 2026.
Abstract Cough is a vital defensive reflex that safeguards the airways; however, it can become maladaptive and pathological. Chronic cough (>8 weeks in duration) affects up to 10% of the global adult population and is associated with considerable health status impairment. The understanding of cough physiology remains limited.
James C. Brown, Katherine L. Rhatigan, Oliver J. Price, Peter S. P. Cho   +3 more
wiley   +1 more source

A non-canonical ARMS-GABARAP interaction modulates dendritic spine formation and synaptic development. [PDF]

EMBO J
Jiang W, Ye J, Chen J, Wang X, Li Y, Li J, Mei Y, Lyu Y, Hu W, Wang C.   +9 more
europepmc   +1 more source

Reframing the axon initial segment: Giant ankyrin-G as a modulator of excitability and plasticity in neurodevelopment. [PDF]

Proc Natl Acad Sci U S A
Lopez AY, Jenkins PM.
europepmc   +1 more source

Tankyrases and Their Binding Proteins: Origins of Their Roles in Diverse Cellular Pathways. [PDF]

Cells
Chalabi Hagkarim N, Grand RJ.
europepmc   +1 more source

A novel <i>ANK1</i> gene mutation associated with hereditary spherocytosis: a case report. [PDF]

Front Pediatr
Lai M, Luo Z, Yang Z, Pan R, Huang W, Zhang W, Ma G, Chen R.   +7 more
europepmc   +1 more source

Molecular Aspects of the Emergence of Monkeypox Virus Clades. [PDF]

Viruses
Babkin IV, Babkina IN, Tikunova NV.
europepmc   +1 more source