Results 141 to 150 of about 30,181 (241)

Ankyrin-G Regulates Forebrain Connectivity and Network Synchronization via Interaction with GABARAP

, 2018
GABAergic circuits are critical for the synchronization and higher order function of brain networks, and defects in this circuitry are linked to neuropsychiatric diseases, including bipolar disorder, schizophrenia, and autism.
C Wang, KS Jones, JC Rodríguez Díaz, V Bennett, LF Lopez-Santiago, KK Walder, M Zhang, PM Jenkins, LL Isom, MG McInnis, AD Nelson, RN Caballero-Florán, J Li, K Chen   +13 more
core   +1 more source

Location of the axon initial segment assembly can be predicted from neuronal shape

iScience
Summary: The axon initial segment (AIS) is located at the proximal axon demarcating the boundary between axonal and somatodendritic compartments. The AIS facilitates the generation of action potentials and maintenance of neuronal polarity. In this study,
Zhuang Xu, Christopher N. Angstmann, Yuhuang Wu, Holly Stefen, Esmeralda Parić, Thomas Fath, Paul M.G. Curmi   +6 more
doaj   +1 more source

Fibroblasts as a Window into the Cell Biology of Ankyrin -B and -G

, 2011
The ankyrin family of proteins form specialized membrane domains in various cell types, including neurons and cardiomyocytes but little is known about how this process occurs. The majority of ankyrins localize to the plasma membrane in these cells while
Dowless, Kayla M.
core  

The Effect of Traumatic Brain Injury on Expression Levels of Ankyrin-G in the Corpus Callosum and Cerebral Cortex

, 2005
The ankyrins comprise a family of proteins serving as components of the membrane cytoskeleton, and participate in a diverse set of associations with multiple binding partners including the cytoplasmic domains of transporters, ion channels, some classes ...
Vanderveer, Andrew S.
core   +1 more source

TMEM16A channel signalling microdomains in the regulation of vascular function

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of TMEM16A channel signalling microdomains. Calcium influx or calcium release from the endoplasmic/sarcoplasmic reticulum (ER/SR) activates TMEM16A channels through interactions with regulatory proteins in vascular smooth muscle cells or endothelial cells. TMEM16A channel activation drives chloride efflux,
Fênix Araujo, Swapnil K. Sonkusare
wiley   +1 more source

Crystal structure of Ankyrin-G in complex with a fragment of Neurofascin reveals binding mechanisms required for integrity of the axon initial segment. [PDF]

J Biol Chem, 2022
He L, Jiang W, Li J, Wang C.
europepmc   +1 more source

Ankyrin G Expression Regulates Apical Delivery of the Epithelial Sodium Channel (ENaC)

, 2019
Research paper describing the interaction of the epithelial sodium channel (ENaC) and the scaffolding protein ankyrin G (AnkG) in renal collecting duct ...
Lindsay Kighlinger (6428990), Xiaoning Liu (588784), Robert S. Edinger (131846), Christine A Klemens (6428988), Michael B. Butterworth (131855)   +4 more
core   +1 more source

Anatomical and functional mapping of vagal nociceptive sensory nerve subsets innervating the mouse lower airways by intersectional genetics

The Journal of Physiology, EarlyView.
Abstract figure legend We used an intersectional approach with recombinase‐expressing mice and adeno‐associated virus to map and modulate distinct nociceptive afferents in the vagal ganglia. TRPV1+P2X2+ neurons resided in the nodose ganglion (N), innervated the lungs (many projected into the alveoli) but not the trachea, and projected to the nucleus ...
Mayur J. Patil, Justin Shane Hooper, Seol‐Hee Kim, Parmvir K. Bahia, Nika Pavelkova, Sanjay S. Nair, Teresa S. Darcey, Karina V. Lurye, Meghana Madaram, Jailene Fiallo, Stephen H. Hadley, Thomas E. Taylor‐Clark   +11 more
wiley   +1 more source

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

The Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer, Wafa Douzi, Johannes Burtscher   +2 more
wiley   +1 more source

Mechanistic studies of ankyrin autoinhibition and ankyrin-spectrin complex formation

, 2017
Ankyrins coordinate with spectrins in excitable or mechano-resistant tissues/cells to organize various functional membrane domains, and thereby to promote structural stabilities and to regulate physiological activities including fast signaling in heart ...
Chen, Keyu
core