Results 111 to 120 of about 1,875 (199)

Interactive segmentation of membrane and membrane‐mimic densities in cryo‐EM maps

Acta Crystallographica Section D, Volume 82, Issue 8, Page 848-861, August 2026.
SURFER performs automated segmentation of contextual membrane and membrane‐mimic density in cryo‐EM maps to enable robust separation of macromolecular signal from surrounding detergent or lipid–membrane features. It is conveniently distributed as a plugin for UCSF ChimeraX, allowing interactive application within standard map‐visualization workflows ...
Alok Bharadwaj, Lotte Veerbeek, Arjen Jakobi   +2 more
wiley   +1 more source

Crystal structure of Ankyrin-G in complex with a fragment of Neurofascin reveals binding mechanisms required for integrity of the axon initial segment. [PDF]

J Biol Chem, 2022
He L, Jiang W, Li J, Wang C.
europepmc   +1 more source

Replacement soaking for human tankyrase 2 enables studies on substrate analogues and inhibitors

Acta Crystallographica Section D, Volume 82, Issue 8, Page 998-1008, August 2026.
Replacement soaking, also known as cross‐soaking, is a compelling method for solving complex structures in cases where traditional soaking and co‐crystallization approaches fail. This method is demonstrated with human tankyrase 2, and new crystal structures of complexes with nanomolar inhibitors and an analogue of the substrate NAD+ are reported ...
Johan Pääkkönen, Sven T. Sowa, Chiara Bosetti, Lari Lehtiö   +3 more
wiley   +1 more source

Cytoskeletal scaffolding of Na_Vs and K_Vs in neocortical pyramidal neurons: Implications for neuronal signaling and plasticity. [PDF]

Curr Opin Cell Biol
Elvira CC, Jenkins PM.
europepmc   +1 more source

Optimal 1TEL–target protein linker character is target protein‐dependent. Corrigendum

Acta Crystallographica Section D, Volume 82, Issue 8, Page 1009-1009, August 2026.
The article by Pedroza Romo et al.[(2026), Acta Cryst. D82, 516–532] is corrected.The name of one of the authors in the article by Pedroza Romo et al.[(2026), Acta Cryst. D82, 516–532] is corrected.
Maria J. Pedroza Romo, Alihikaua Keliiliki, Jacob C. Averett, Joseph F. Gonzalez, Ethan Noakes, Elijah W. Wilson, Conrad Smith, Blake Averett, Dalton Hansen, Riley Nickles, Miles Bradford, Sara Soleimani, Tobin Smith, Supeshala Nawarathnage, Prasadika Samarawickrama, Ariel Kelsch, Derick Bunn, Cameron Stewart, Wisdom Abiodun, Evan Tsubaki, Seth Brown, Tzanko I. Doukov, James D. Moody   +22 more
wiley   +1 more source

De novo mutations in ANK1 and SPTB cause hereditary spherocytosis: three case reports and literature review. [PDF]

Ann Hematol
Qin Y, Lu L, Huang X, Li W, Qin Y, Tang S, Wei S.   +6 more
europepmc   +1 more source

Ankyrin-dependent Na⁺ channel clustering prevents neuromuscular synapse fatigue. [PDF]

Curr Biol, 2021
Zhang C, Joshi A, Liu Y, Sert O, Haddix SG, Teliska LH, Rasband A, Rodney GG, Rasband MN.   +8 more
europepmc   +1 more source

Contact sensitisers activate keratinocytes and induce cytotoxicity via Transient Receptor Potential Ankyrin 1 in allergic contact dermatitis

British Journal of Pharmacology, Volume 183, Issue 16, Page 4610-4627, August 2026.
Abstract Background and Purpose Allergic contact dermatitis (ACD) is a frequent inflammatory skin disease with limited therapeutic options. While neuronal Transient Receptor Potential Ankyrin 1 (TRPA1) has been implicated in ACD, the role of keratinocyte TRPA1 remains unclear.
Areej Jaber, Szabina Horváth, Balázs Zoltán Zsidó, Viktória Kormos, János Konkoly, Csaba Hetényi, Erika Pintér, Ágnes Kemény, Rolland Gyulai   +8 more
wiley   +1 more source

Loss of ANK3 Function Causes a Recessive Neurodevelopmental Disorder with Cerebellar Ataxia. [PDF]

Mov Disord
Maroofian R, Spoto G, Moualek D, Zaki MS, Biswas A, D'Arco F, Biglari S, Nikuei P, Gleeson JG, Tazir M, Ali Pacha L, Houlden H.   +11 more
europepmc   +1 more source

Ankyrin Repeat [PDF]

, 2020
openaire   +1 more source