Results 1 to 10 of about 36,997 (223)

Poxviral Ankyrin Proteins [PDF]

open access: yesViruses, 2015
Multiple repeats of the ankyrin motif (ANK) are ubiquitous throughout the kingdoms of life but are absent from most viruses. The main exception to this is the poxvirus family, and specifically the chordopoxviruses, with ANK repeat proteins present in all
Christopher Squire   +2 more
exaly   +5 more sources

Ankyrin‐2 genetic variants: A case of Ankyrin‐B syndrome [PDF]

open access: yesAnnals of Noninvasive Electrocardiology, 2022
Inherited cardiac arrhythmias (ICA) have become one of the leading causes of sudden cardiac death in people under 40 years old. Variants in the ankyrin‐B or ankyrin‐2 genes will result in several cardiac arrhythmias ranging from sinus node dysfunction to
Bryan Richard Sasmita
exaly   +4 more sources

Wolbachia uses ankyrin repeats to target specific fly proteins [PDF]

open access: yesmBio
Arthropods, the most diverse phylum on Earth, are hosts to a plethora of bacterial parasites that secrete various effectors of unknown function during infection. The most prevalent of these is the intracellular bacterium Wolbachia pipientis.
William Hamilton   +5 more
doaj   +2 more sources

The varied functions of the giant muscle scaffold protein obscurin [PDF]

open access: yesFrontiers in Cell and Developmental Biology
Obscurin is a giant protein encoded by the OBSCN gene in human myocytes, known for its roles in sarcomere organization, elasticity, stretch response, and myofibrillogenesis.
James Novac Di Paola, Frieder Schöck
doaj   +2 more sources

Sequence and Structure-Based Analyses of Human Ankyrin Repeats

open access: yesMolecules, 2022
Ankyrin is one of the most abundant protein repeat families found across all forms of life. It is found in a variety of multi-domain and single domain proteins in humans with diverse number of repeating units.
Broto Chakrabarty   +2 more
exaly   +3 more sources

The Diversity and Evolution of Wolbachia Ankyrin Repeat Domain Genes [PDF]

open access: yesPLoS ONE, 2013
Ankyrin repeat domain-encoding genes are common in the eukaryotic and viral domains of life, but they are rare in bacteria, the exception being a few obligate or facultative intracellular Proteobacteria species.
Henk Braig   +2 more
exaly   +2 more sources

Ankyrin-G and Its Binding Partners in Neurons: Orchestrating the Molecular Structure of the Axon Initial Segment [PDF]

open access: yesBiomolecules
The axon initial segment (AIS) is a specialized subcellular domain that plays an essential role in action potential initiation and the diffusion barrier.
Xiaowei Zhu   +4 more
doaj   +2 more sources

Specific Interaction of DARPin with HIV-1 CANTD Disturbs the Distribution of Gag, RNA Packaging, and Tetraspanin Remodelling in the Membrane

open access: yesViruses, 2022
A designed repeat scaffold protein (AnkGAG1D4) recognizing the human immunodeficiency virus-1 (HIV-1) capsid (CA) was formerly established with antiviral assembly. Here, we investigated the molecular mechanism of AnkGAG1D4 function during the late stages
Sutpirat Moonmuang   +6 more
doaj   +1 more source

Ankyrin-B is lipid-modified by S-palmitoylation to promote dendritic membrane scaffolding of voltage-gated sodium channel NaV1.2 in neurons

open access: yesFrontiers in Physiology, 2023
Neuronal ankyrin-B is an intracellular scaffolding protein that plays multiple roles in the axon. By contrast, relatively little is known about the function of ankyrin-B in dendrites, where ankyrin-B is also localized in mature neurons.
Julie P. Gupta   +2 more
doaj   +1 more source

Molecular Mechanisms of L1 and NCAM Adhesion Molecules in Synaptic Pruning, Plasticity, and Stabilization

open access: yesFrontiers in Cell and Developmental Biology, 2021
Mammalian brain circuits are wired by dynamic formation and remodeling during development to produce a balance of excitatory and inhibitory synapses. Synaptic regulation is mediated by a complex network of proteins including immunoglobulin (Ig)- class ...
Bryce W. Duncan   +2 more
doaj   +1 more source

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