Results 21 to 30 of about 36,997 (223)
eLife, 2021 Neuronal ankyrins cluster and link membrane proteins to the actin and spectrin-based cytoskeleton. Among the three vertebrate ankyrins, little is known about neuronal Ankyrin-R (AnkR). We report AnkR is highly enriched in Pv+ fast-spiking interneurons in
Sharon R Stevens +10 more
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Frontiers in Cell and Developmental Biology, 2016 Cell adhesion molecules of the immunoglobulin superfamily (IgSF) including the neural cell adhesion molecule (NCAM) and members of the L1 family of neuronal cell adhesion molecules play important functions in the developing nervous system by regulating ...
Vladimir eSytnyk, Iryna eLeshchyns'Ka
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Frontiers in Neuroanatomy, 2023 A novel function for the L1 cell adhesion molecule, which binds the actin adaptor protein Ankyrin was identified in constraining dendritic spine density on pyramidal neurons in the mouse neocortex.
Kelsey E. Murphy +17 more
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Ophthalmic Research, 2009 Ankyrin was identified in the human, bovine and chicken lens as a protein of molecular weight 216 kilodaltons. It is specifically extracted from association with the fiber cell plasma membranes by high-ionic-strength salt solution and is predominantly found in young fiber cells.
A, Dola, M, Katar, P, Hussain, H, Maisel
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Pleiotropic Ankyrins: Scaffolds for Ion Channels and Transporters
Channels, 2022 The ankyrin proteins (Ankyrin-R, Ankyrin-B, and Ankyrin-G) are a family of scaffolding, or membrane adaptor proteins necessary for the regulation and targeting of several types of ion channels and membrane transporters throughout the body.
Sharon R. Stevens, Matthew N. Rasband
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Virology Journal, 2011 Background The carboxyl terminal of Epstein-Barr virus (EBV) ZEBRA protein (also termed BZLF-1 encoded replication protein Zta or ZEBRA) binds to both NF-κB and p53. The authors have previously suggested that this interaction results from an ankyrin-like
Ghoda Lucy Y +3 more
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Spherocytosis-Related L1340P Mutation in Ankyrin Affects Its Interactions with Spectrin
Life, 2023 Previously, we reported a new missense mutation in the ANK1 gene that correlated with the hereditary spherocytosis phenotype. This mutation, resulting in L1340P substitution (HGMD CM149731), likely leads to the changes in the conformation of the ankyrin ...
Beata Machnicka +4 more
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Nanospring behaviour of ankyrin repeats [PDF]
Nature, 2006 Ankyrin repeats are an amino-acid motif believed to function in protein recognition; they are present in tandem copies in diverse proteins in nearly all phyla. Ankyrin repeats contain antiparallel alpha-helices that can stack to form a superhelical spiral. Visual inspection of the extrapolated structure of 24 ankyrin-R repeats indicates the possibility
Gwangrog, Lee +5 more
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PLoS Biology, 2005 We report identification of an ankyrin-B-based macromolecular complex of Na/K ATPase (alpha 1 and alpha 2 isoforms), Na/Ca exchanger 1, and InsP3 receptor that is localized in cardiomyocyte T-tubules in discrete microdomains distinct from classic ...
Peter J Mohler +2 more
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Ankyrins and Spectrins in Cardiovascular Biology and Disease
Frontiers in Physiology, 2017 Ankyrins are adaptor proteins critical for the expression and targeting of cardiac membrane proteins, signaling molecules, and cytoskeletal elements.
Mona M. El Refaey +4 more
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