Results 31 to 40 of about 42,034 (274)

Pleiotropic Ankyrins: Scaffolds for Ion Channels and Transporters

Channels, 2022
The ankyrin proteins (Ankyrin-R, Ankyrin-B, and Ankyrin-G) are a family of scaffolding, or membrane adaptor proteins necessary for the regulation and targeting of several types of ion channels and membrane transporters throughout the body.
Sharon R. Stevens, Matthew N. Rasband
doaj   +1 more source

Ankyrin repeat domain-encoding genes in the wPip strain of Wolbachia from the Culex pipiens group [PDF]

, 2007
BACKGROUND: Wolbachia are obligate endosymbiotic bacteria maternally transmitted through the egg cytoplasm that are responsible for several reproductive disorders in their insect hosts, such as cytoplasmic incompatibility (CI) in infected mosquitoes ...
Parkhill Julian, Sinkins, Steven P., Thomson Nicholas R, Sanders, Mandy J, Klasson Lisa, Walker, T, Sanders, MJ, Sebaihia, M, Parkhill, J, Sinkins Steven P, Klasson, L, Sanders, Mandy J., Klasson, Lisa, Thompson, Nicholas R., Sinkins, Steven P, Sanders Mandy J, Sebaihia, Mohammed, Sebalhia, Mohammed, Parkhill, Julian, Walker, Thomas, Thomson, Nicholas R, Walker Thomas, Thomson, Nicholas R., Sinkins, SP, Sebaihia Mohammed, Thomson, NR   +25 more
core   +1 more source

Analysis of an ankyrin-like region in Epstein Barr Virus encoded (EBV) BZLF-1 (ZEBRA) protein: implications for interactions with NF-κB and p53

Virology Journal, 2011
Background The carboxyl terminal of Epstein-Barr virus (EBV) ZEBRA protein (also termed BZLF-1 encoded replication protein Zta or ZEBRA) binds to both NF-κB and p53. The authors have previously suggested that this interaction results from an ankyrin-like
Ghoda Lucy Y, Liu Yang, Dreyfus David H, Chang Joseph T   +3 more
doaj   +1 more source

Spherocytosis-Related L1340P Mutation in Ankyrin Affects Its Interactions with Spectrin

Life, 2023
Previously, we reported a new missense mutation in the ANK1 gene that correlated with the hereditary spherocytosis phenotype. This mutation, resulting in L1340P substitution (HGMD CM149731), likely leads to the changes in the conformation of the ankyrin ...
Beata Machnicka, Aleksander Czogalla, Dżamila M. Bogusławska, Piotr Stasiak, Aleksander F. Sikorski   +4 more
doaj   +1 more source

Ankyrin-B coordinates the Na/K ATPase, Na/Ca exchanger, and InsP3 receptor in a cardiac T-tubule/SR microdomain.

PLoS Biology, 2005
We report identification of an ankyrin-B-based macromolecular complex of Na/K ATPase (alpha 1 and alpha 2 isoforms), Na/Ca exchanger 1, and InsP3 receptor that is localized in cardiomyocyte T-tubules in discrete microdomains distinct from classic ...
Peter J Mohler, Jonathan Q Davis, Vann Bennett   +2 more
doaj   +2 more sources

Ankyrins and Spectrins in Cardiovascular Biology and Disease

Frontiers in Physiology, 2017
Ankyrins are adaptor proteins critical for the expression and targeting of cardiac membrane proteins, signaling molecules, and cytoskeletal elements.
Mona M. El Refaey, Mona M. El Refaey, Peter J. Mohler, Peter J. Mohler, Peter J. Mohler   +4 more
doaj   +1 more source

Developmental mechanism of the periodic membrane skeleton in axons

eLife, 2014
Actin, spectrin, and associated molecules form a periodic sub-membrane lattice structure in axons. How this membrane skeleton is developed and why it preferentially forms in axons are unknown.
Guisheng Zhong, Jiang He, Ruobo Zhou, Damaris Lorenzo, Hazen P Babcock, Vann Bennett, Xiaowei Zhuang   +6 more
doaj   +1 more source

Cardiac ankyrins in health and disease [PDF]

Journal of Molecular and Cellular Cardiology, 2009
Ankyrins are critical components of ion channel and transporter signaling complexes in the cardiovascular system. Over the past 5 years, ankyrin dysfunction has been linked with abnormal ion channel and transporter membrane organization and fatal human arrhythmias.
Seyed M, Hashemi, Thomas J, Hund, Peter J, Mohler   +2 more
openaire   +2 more sources

β-III spectrin underpins ankyrin R function in Purkinje cell dendritic trees:Protein complex critical for sodium channel activity is impaired by SCA5-associated mutations

, 2014
Beta III spectrin is present throughout the elaborate dendritic tree of cerebellar Purkinje cells and is required for normal neuronal morphology and cell survival.
Perkins, Emma M., Clarkson, Yvonne L., Lyndon, Alastair R., Skehel, Paul A., Jackson, Mandy, Cairncross, Callum J., Lyndon, Alastair R.; id_orcid   +6 more
core   +1 more source

Identification and characterization of cell adhesion molecules controlling synapse stability [PDF]

, 2012
Neuronal circuits form the basis of a functional nervous system to process and integrate information and to react to environmental cues. The formation of functional synaptic connections between neurons is essential for the establishment of these circuits.
Enneking, Eva-Maria
core   +1 more source