Results 11 to 20 of about 42,034 (274)
Poxviral Ankyrin Proteins [PDF]
Viruses, 2015 Multiple repeats of the ankyrin motif (ANK) are ubiquitous throughout the kingdoms of life but are absent from most viruses. The main exception to this is the poxvirus family, and specifically the chordopoxviruses, with ANK repeat proteins present in all
Michael H. Herbert +2 more
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Ankyrin‐2 genetic variants: A case of Ankyrin‐B syndrome [PDF]
Annals of Noninvasive Electrocardiology, 2022 Inherited cardiac arrhythmias (ICA) have become one of the leading causes of sudden cardiac death in people under 40 years old. Variants in the ankyrin‐B or ankyrin‐2 genes will result in several cardiac arrhythmias ranging from sinus node dysfunction to
Jin Song +2 more
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Mechanical Anisotropy of Ankyrin Repeats [PDF]
Biophysical Journal, 2012 Red blood cells are frequently deformed and their cytoskeletal proteins such as spectrin and ankyrin-R are repeatedly subjected to mechanical forces. While the mechanics of spectrin was thoroughly investigated in vitro and in vivo, little is known about the mechanical behavior of ankyrin-R.
Lee, W +7 more
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Mechanical Unfolding of an Ankyrin Repeat Protein [PDF]
Biophysical Journal, 2010 Ankryin repeat proteins comprise tandem arrays of a 33-residue, predominantly alpha-helical motif that stacks roughly linearly to produce elongated and superhelical structures. They function as scaffolds mediating a diverse range of protein-protein interactions, and some have been proposed to play a role in mechanical signal transduction processes in ...
Serquera D. +5 more
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Nanospring behaviour of ankyrin repeats [PDF]
Nature, 2006 Ankyrin repeats are an amino-acid motif believed to function in protein recognition; they are present in tandem copies in diverse proteins in nearly all phyla. Ankyrin repeats contain antiparallel alpha-helices that can stack to form a superhelical spiral. Visual inspection of the extrapolated structure of 24 ankyrin-R repeats indicates the possibility
Gwangrog, Lee +5 more
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FEBS Letters, 2000 This review is focused on ankyrin which is a protein linker between the integral membrane proteins and spectrin‐based cytoskeleton. Structure and distribution of different ankyrin isoforms that are products of alternative‐spliced genes are described. Interaction of ankyrins with various membranes is considered.
Rubtsov, Alexander M, Lopina, Olga D
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Severe hereditary spherocytosis presenting with non-immune fetal hydrops
Indian Pediatrics Case Reports, 2023 Background: Hereditary spherocytosis (HS) is characterized by spherocytes on the peripheral smear and heterogeneous clinical presentation (mild, moderate, moderate/severe, and severe) depending upon the severity of hemolytic anemia, jaundice, and ...
Snehal Mallakmir +3 more
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Frontiers in Cellular and Infection Microbiology, 2023 The emerging and ongoing outbreak of human monkeypox (hMPX) in 2022 is a serious global threat. An understanding of the evolution of the monkeypox virus (MPXV) at the single-gene level may provide clues for exploring the unique aspects of the current ...
Xiao-Yong Zhan, Gao-Feng Zha, Yulong He
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Biomolecules, 2021 Previously, a designed ankyrin repeat protein, AnkGAG1D4, was generated for intracellular targeting of the HIV-1 capsid domain. The efficiency was satisfactory in interfering with the HIV assembly process.
Kanokporn Sornsuwan +7 more
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Regulation of Cardiac Conduction and Arrhythmias by Ankyrin/Spectrin-Based Macromolecular Complexes
Journal of Cardiovascular Development and Disease, 2021 The cardiac conduction system is an extended network of excitable tissue tasked with generation and propagation of electrical impulses to signal coordinated contraction of the heart.
Drew Nassal +6 more
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