Results 51 to 60 of about 2,806 (200)
Frontiers in Cellular Neuroscience, 2017 Neurons are highly specialized cells of the nervous system that receive, process and transmit electrical signals critical for normal brain function.
Andrew D. Nelson +2 more
doaj +1 more source
Investigating the role of histone deacetylase HDAC4 in long-term memory formation : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Genetics at Massey University, Manawatu, New Zealand [PDF]
, 2016 Listed in 2017 Dean's List of Exceptional ThesesEpigenetic mechanisms are emerging as master regulators of cognitive abilities such as learning and memory.
Schwartz, Silvia
core
Advances in the design and engineering of peptide-binding repeat proteins [PDF]
, 2017 The specific recognition of peptides, which we define to include unstructured regions or denatured forms of proteins, is an intrinsic part of a multitude of biochemical assays and procedures. Many cellular interactions are also based on this principle as
Ernst, Patrick, Plückthun, Andreas
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Multifunctional protein: cardiac ankyrin repeat protein [PDF]
Journal of Zhejiang University-SCIENCE B, 2016 Cardiac ankyrin repeat protein (CARP) not only serves as an important component of muscle sarcomere in the cytoplasm, but also acts as a transcription co-factor in the nucleus. Previous studies have demonstrated that CARP is up-regulated in some cardiovascular disorders and muscle diseases; however, its role in these diseases remains controversial now.
Na, Zhang, Xiao-Jie, Xie, Jian-An, Wang
openaire +2 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
On the Teneurin track: a new synaptic organization molecule emerges [PDF]
, 2015 To achieve proper synaptic development and function, coordinated signals must pass between the pre- and postsynaptic membranes. Such transsynaptic signals can be comprised of receptors and secreted ligands, membrane associated receptors, and also pairs ...
Timothy J. Mosca
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Ophthalmic Research, 1990 Ankyrin was identified in the human, bovine and chicken lens as a protein of molecular weight 216 kilodaltons. It is specifically extracted from association with the fiber cell plasma membranes by high-ionic-strength salt solution and is predominantly found in young fiber cells.
A, Dola, M, Katar, P, Hussain, H, Maisel
openaire +2 more sources
Advanced Science, EarlyView.Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian +5 more
wiley +1 more source
Deep conservation of human protein tandem repeats within the eukaryotes [PDF]
, 2014 Tandem repeats (TRs) are a major element of protein sequences in all domains of life. They are particularly abundant in mammals, where by conservative estimates one in three proteins contain a TR. High generation-scale duplication and deletion rates were
Anisimova, Maria +2 more
core +5 more sources
Virology Journal, 2011 Background The carboxyl terminal of Epstein-Barr virus (EBV) ZEBRA protein (also termed BZLF-1 encoded replication protein Zta or ZEBRA) binds to both NF-κB and p53. The authors have previously suggested that this interaction results from an ankyrin-like
Ghoda Lucy Y +3 more
doaj +1 more source