Results 31 to 40 of about 2,018 (241)
Nanospring behaviour of ankyrin repeats [PDF]
Nature, 2006 Ankyrin repeats are an amino-acid motif believed to function in protein recognition; they are present in tandem copies in diverse proteins in nearly all phyla. Ankyrin repeats contain antiparallel alpha-helices that can stack to form a superhelical spiral. Visual inspection of the extrapolated structure of 24 ankyrin-R repeats indicates the possibility
Gwangrog, Lee +5 more
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Cardiac ankyrins in health and disease [PDF]
Journal of Molecular and Cellular Cardiology, 2009 Ankyrins are critical components of ion channel and transporter signaling complexes in the cardiovascular system. Over the past 5 years, ankyrin dysfunction has been linked with abnormal ion channel and transporter membrane organization and fatal human arrhythmias.
Seyed M, Hashemi +2 more
openaire +2 more sources
BMC Genetics, 2010 Background Recent QTL and gene expression studies have highlighted ankyrins as positional and functional candidate genes for meat quality. Our objective was to characterise the promoter region of the bovine ankyrin 1 gene and to test polymorphisms for ...
Sweeney Torres +3 more
doaj +1 more source
LQT4 Gene: The "Missing" Ankyrin [PDF]
Molecular Interventions, 2003 Mutations in ion channels have been implicated in the formation of long QT syndrome (LQTS). However, Mohler et al. have recently uncovered a role for ankyrin-B, a non-ion channel protein, in type IV LQTS. Calcium signalling is altered, and the functions of several channels and pumps that normally interact with wild-type ankyrin-B are impaired in the ...
Sandro, Yong, Xiaoli, Tian, Qing, Wang
openaire +2 more sources
Evolution and comparative genomics of the most common Trichoderma species
BMC Genomics, 2019 Background The growing importance of the ubiquitous fungal genus Trichoderma (Hypocreales, Ascomycota) requires understanding of its biology and evolution. Many Trichoderma species are used as biofertilizers and biofungicides and T.
Christian P. Kubicek +16 more
doaj +1 more source
PLOS Genetics, 2021 The number of grains per panicle is an important yield-related trait in cereals which depends in part on panicle branching complexity. One component of this complexity is the number of secondary branches per panicle. Previously, a GWAS site associated with secondary branch and spikelet numbers per panicle in rice was identified.
Giang Ngan Khong +11 more
openaire +5 more sources
Ankyrins are highly conserved between bilaterians, cnidarians and placozoans.
, 2016 (A) schematic diagram of a canonical ankyrin protein showing the 24 ankyrin repeats, the ZU5-ZU5-UPA cassette and the death domain (DD). The position of the long exon included in giant isoforms is shown for vertebrates (red star) and protostome ...
Melissa M. Rolls (3375224) +9 more
core +1 more source
Obscurins: Goliaths and Davids take over non-muscle tissues.
PLoS ONE, 2014 Obscurins comprise a family of proteins originally identified in striated muscles, where they play essential roles in myofibrillogenesis, cytoskeletal organization, and Ca(2+) homeostasis.
Maegen A Ackermann +4 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Frontiers in Cellular Neuroscience, 2017 Neurons are highly specialized cells of the nervous system that receive, process and transmit electrical signals critical for normal brain function.
Andrew D. Nelson +2 more
doaj +1 more source