Results 21 to 30 of about 1,875 (199)
Antiviral activity of recombinant ankyrin targeted to the capsid domain of HIV-1 Gag polyprotein
Retrovirology, 2012 Background Ankyrins are cellular mediators of a number of essential protein-protein interactions. Unlike intrabodies, ankyrins are composed of highly structured repeat modules characterized by disulfide bridge-independent folding.
Nangola Sawitree +8 more
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Polydnaviral ankyrin proteins aid parasitic wasp survival by coordinate and selective inhibition of hematopoietic and immune NF-kappa B signaling in insect hosts. [PDF]
PLoS Pathogens, 2013 Polydnaviruses are mutualists of their parasitoid wasps and express genes in immune cells of their Lepidopteran hosts. Polydnaviral genomes carry multiple copies of viral ankyrins or vankyrins.
Gwenaelle Gueguen +4 more
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Mechanisms underlying the role of ankyrin-B in cardiac and neurological health and disease
Frontiers in Cardiovascular Medicine, 2022 The ANK2 gene encodes for ankyrin-B (ANKB), one of 3 members of the ankyrin family of proteins, whose name is derived from the Greek word for anchor. ANKB was originally identified in the brain (B denotes “brain”) but has become most widely known for its
Nicole S. York +7 more
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Structural basis of diverse membrane target recognitions by ankyrins
eLife, 2014 Ankyrin adaptors together with their spectrin partners coordinate diverse ion channels and cell adhesion molecules within plasma membrane domains and thereby promote physiological activities including fast signaling in the heart and nervous system ...
Chao Wang +6 more
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Frontiers in Cell and Developmental Biology, 2019 The structural integrity of synaptic connections critically depends on the interaction between synaptic cell adhesion molecules (CAMs) and the underlying actin and microtubule cytoskeleton.
Tobias Weber +3 more
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Ophthalmic Research, 2009 Ankyrin was identified in the human, bovine and chicken lens as a protein of molecular weight 216 kilodaltons. It is specifically extracted from association with the fiber cell plasma membranes by high-ionic-strength salt solution and is predominantly found in young fiber cells.
A, Dola, M, Katar, P, Hussain, H, Maisel
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Axonal Spectrins: Nanoscale Organization, Functional Domains and Spectrinopathies
Frontiers in Cellular Neuroscience, 2019 Spectrin cytoskeletons are found in all metazoan cells, and their physical interactions between actin and ankyrins establish a meshwork that provides cellular structural integrity.
Cheng-Hsin Liu +2 more
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Nanospring behaviour of ankyrin repeats [PDF]
Nature, 2006 Ankyrin repeats are an amino-acid motif believed to function in protein recognition; they are present in tandem copies in diverse proteins in nearly all phyla. Ankyrin repeats contain antiparallel alpha-helices that can stack to form a superhelical spiral. Visual inspection of the extrapolated structure of 24 ankyrin-R repeats indicates the possibility
Gwangrog, Lee +5 more
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Cardiac ankyrins in health and disease [PDF]
Journal of Molecular and Cellular Cardiology, 2009 Ankyrins are critical components of ion channel and transporter signaling complexes in the cardiovascular system. Over the past 5 years, ankyrin dysfunction has been linked with abnormal ion channel and transporter membrane organization and fatal human arrhythmias.
Seyed M, Hashemi +2 more
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BMC Genetics, 2010 Background Recent QTL and gene expression studies have highlighted ankyrins as positional and functional candidate genes for meat quality. Our objective was to characterise the promoter region of the bovine ankyrin 1 gene and to test polymorphisms for ...
Sweeney Torres +3 more
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