Results 121 to 130 of about 172,471 (314)

The Ca2+- and phospholipid-binding protein Annexin A2 is able to increase and decrease plasma membrane order

, 2021
Svetlana Varyukhina, Antonin Lamazière, J. Delaunay, Anaëlle de Wreede, Jesús Ayala‐Sanmartín   +4 more
openalex   +2 more sources

Halofuginone is a Molecular Glue Degrader of Integrin β4

Advanced Science, EarlyView.
Integrin β4 overexpression is linked to aggressive tumors and poor prognosis, but targeted therapies are lacking. We identified halofuginone (HF) as a molecular glue degrader that promotes integrin β4 degradation via the CRL4BWDR18 E3 ligase. HF suppresses tumor progression in vitro and in vivo, offering a new strategy for targeting oncogenic ...
Wei Gong, Di Yang, Junrui Tian, Yufei Chai, Tiantian Yu, Qingnan Wu, Yan Wang, Weimin Zhang, Qimin Zhan   +8 more
wiley   +1 more source

A calcyclin-associated protein is a newly identified member of the Ca2+/phospholipid-binding proteins, annexin family.

, 1992
Hiroshi Tokumitsu, Akihiro Mizutani, Hideyuki Minami, Ryōji Kobayashi, Hisashi Hidaka   +4 more
openalex   +1 more source

Disulfide‐Bridged Ru Complex–Mediated Photo‐Disulfidptosis for Colorectal Cancer Therapy

Advanced Science, EarlyView.
In this work, a binuclear ruthenium complex, RuSSRu was developed for efficient colorectal cancer (CRC) treatment. The synergistic interaction between disulfidptosis and lysosomal damage‐induced apoptosis induced by RuSSRu amplified tumor cell death. This innovative approach offers a potent therapeutic strategy for CRC.
Simeng He, Wendong Jin, Jiaojiao Pang, Xiaoting Gong, Shixian Cao, Duo Mao, Yuguo Chen, Kang‐Nan Wang, Bin Liu   +8 more
wiley   +1 more source

Calcium-binding proteins annexin A2 and S100A6 are sensors of tubular injury and recovery in acute renal failure [PDF]

, 2005
Chao‐Wen Cheng, Abdalla Rifai, Shuk‐Man Ka, Hao‐Ai Shui, Yuh‐Feng Lin, Wei‐Hwa Lee, Ann Chen   +6 more
openalex   +1 more source

A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes

Advanced Science, EarlyView.
We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen, Zixing Xu, Zerun Hao, Yanming Chen, Kai Xie, Haofan Yin, Xueying Wang, Jie Min, Sihan Sun, Baiding Chen, Chengxiu Ling, Mingming Xu, Yizhao Chen, Gang Ruan   +13 more
wiley   +1 more source

Inhibition of triple negative and herceptin-resistant breast cancer proliferation and migration by annexin A2 antibodies [PDF]

, 2015
Jamboor K. Vishwanatha, Pankaj Chaudhary
openalex   +1 more source

GALNT10 Affects O‐Glycosylation of IGFBP7 to Promote Tumor Vascular Remodeling and Metastasis of Ovarian Cancer

Advanced Science, EarlyView.
The glycosyltransferase GALNT10 facilitates ovarian cancer metastasis through the induction of tumor cell EMT and tumor vascular dysfunction. GALNT10 enhanced the extracellular secretion of IGFBP7 through O‐GalNAc glycosylation modification at the T188 site, which subsequently interacts with CD93 on endothelial cells, leading to vascular remodeling ...
Yanan Zhang, Ayala Zuha, Zhangxin Wu, Aiping Luo, Bixia Jin, Qinkun Sun, Yuan Li, Qiyu Liu, Hongyan Guo, Chunliang Shang   +9 more
wiley   +1 more source

Interaction between S100A8/A9 and Annexin A6 Is Involved in the Calcium-induced Cell Surface Exposition of S100A8/A9

, 2008
Günther Bode, Aloys Lüken, Claus Kerkhoff, Johannes Roth, Stephan Ludwig, Wolfgang Nacken   +5 more
openalex   +1 more source

Unmasking the Annexin I Interaction from the Structure of Apo-S100A11 [PDF]

, 2003
Anne C Dempsey, Michael P. Walsh, Gary S. Shaw   +2 more
openalex   +1 more source