Results 11 to 20 of about 172,471 (314)

Design and Synthesis of Newly Synthesized Acrylamide Derivatives as Potential Chemotherapeutic Agents against MCF-7 Breast Cancer Cell Line Lodged on PEGylated Bilosomal Nano-Vesicles for Improving Cytotoxic Activity

open access: yesPharmaceuticals, 2021
Cancer is a multifaceted disease. With the development of multi drug resistance, the need for the arousal of novel targets in order to avoid these drawbacks increased. A new series of acrylamide derivatives was synthesized from starting material 4-(furan-
Islam Zaki   +6 more
doaj   +1 more source

The rice annexin gene OsAnn5 is involved in cold stress tolerance at the seedling stage

open access: yesPlant Direct, 2023
Annexins exist widely in plants as multigene families and play critical roles in stress responses and a range of cellular processes. This study provides a comprehensive account of the cloning and functional characterization of the rice annexin gene ...
Zhiqun Que   +3 more
doaj   +1 more source

Annexins and Endocytosis [PDF]

open access: yesTraffic, 2007
Annexins are calcium‐ and phospholipid‐binding proteins that have been proposed to have multiple roles in membrane traffic. Historically, this has been based on the in vitro properties of annexins and their localization to specific membrane compartments. However, recent functional evidence supports a role for annexins in specific membrane traffic steps,
Clare E, Futter, Ian J, White
openaire   +2 more sources

Annexin-Mediated Calcium Signalling in Plants

open access: yesPlants, 2014
Calcium-permeable channels underpin elevations of free calcium that encode specific signals in stress adaptation, development and immunity. Identifying the genes encoding these channels remains a central goal of plant signalling research.
Julia M. Davies
doaj   +1 more source

Annexins and cardiovascular diseases: Beyond membrane trafficking and repair

open access: yesFrontiers in Cell and Developmental Biology, 2022
Cardiovascular diseases (CVD) remain the leading cause of mortality worldwide. The main cause underlying CVD is associated with the pathological remodeling of the vascular wall, involving several cell types, including endothelial cells, vascular smooth ...
Nerea Méndez-Barbero   +10 more
doaj   +1 more source

‘Annexins’ themed section [PDF]

open access: yesBritish Journal of Pharmacology, 2015
Linked ArticlesThis article is part of a themed section on Annexins VII Programme.
R J, Flower, M, Perretti
openaire   +2 more sources

ER-luminal [Ca2+] regulation of InsP3 receptor gating mediated by an ER-luminal peripheral Ca2+-binding protein

open access: yeseLife, 2020
Modulating cytoplasmic Ca2+ concentration ([Ca2+]i) by endoplasmic reticulum (ER)-localized inositol 1,4,5-trisphosphate receptor (InsP3R) Ca2+-release channels is a universal signaling pathway that regulates numerous cell-physiological processes ...
Horia Vais   +12 more
doaj   +1 more source

Annexin A1, A2 and cytokine levels during experimental sepsis in calves [PDF]

open access: yesThe Iranian Journal of Veterinary Science and Technology, 2017
Annexins are fundamentally related proteins that process a variety of physiologic and pathologic procedures, including suppression of inflammation.
Mohammad Reza Mokhber Dezfouli   +3 more
doaj   +1 more source

Annexins in Glaucoma

open access: yesInternational Journal of Molecular Sciences, 2018
Glaucoma is one of the leading causes of irreversible visual loss, which has been estimated to affect 3.5% of those over 40 years old and projected to affect a total of 112 million people by 2040. Such a dramatic increase in affected patients demonstrates the need for continual improvement in the way we diagnose and treat this condition.
Timothy E. Yap   +4 more
openaire   +5 more sources

Annexin–Actin Interactions [PDF]

open access: yesTraffic, 2004
The actin cytoskeleton is a malleable framework of polymerised actin monomers that may be rapidly restructured to enable diverse cellular activities such as motility, endocytosis and cytokinesis. The regulation of actin dynamics involves the coordinated activity of numerous proteins, among which members of the annexin family of Ca2+‐ and phospholipid ...
Matthew J, Hayes   +3 more
openaire   +2 more sources

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