Results 111 to 120 of about 243,891 (236)
Anti-tumour effects of all-trans retinoid acid on serous ovarian cancer
Background Annexin A2 is increased in serous ovarian cancer and plays an essential role in ovarian cancer invasion and metastasis. In combination with S100A10, annexin A2 plays an important role in the plasminogen activator system regulating plasmin ...
Noor A. Lokman +5 more
doaj +1 more source
ABSTRACT Ultraviolet B (UVB) radiation is a major risk factor for cataract development, but the molecular mechanisms underlying this process, particularly the involvement of regulated cell death pathways such as ferroptosis, remain unclear. Transcriptomic, proteomic, and metabolomic analyses were performed on lens tissues from UVB‐induced cataract rat ...
Fei Xu +4 more
wiley +1 more source
Role of annexin A2 in ovarian cancer metastasis. [PDF]
Ovarian cancer is the most lethal gynaecological cancer. We identified annexin A2 to be modulated in the co-culture of ovarian cancer and peritoneal cells in vitro.
Lokman, Noor Alia
core
Identification of Annexin A2 by MALDI TOF/TOF mass spectrometry.
(A) MS/MS spectra of Annexin A2. (B) Amino acid sequence of Annexin A2. Underlined bold text indicates matched peptide sequences.
Bin Liu (5899) +7 more
core +1 more source
Proteomic Profiling of Myofiber Repair Annexins and Their Role in Duchenne Muscular Dystrophy
ABSTRACT Myofiber regeneration and membrane repair play crucial roles in maintaining the continuous physiological functioning of the neuromuscular system. A swift and efficient repair mechanism enables the rapid restoration of sarcolemmal integrity following cellular impairment in damaged skeletal muscles.
Paul Dowling +6 more
wiley +1 more source
Annexin A2 has been described as an important receptor for tissue-type plasminogen activator in endothelium and other cell types. Interaction between tissue-type plasminogen activator and its cellular receptor is critical for many of the functions of this protease.
Oriol, Roda +5 more
openaire +2 more sources
Annexin A2 Promotes Glioma Cell Invasion and Tumor Progression
Gliomas are highly invasive, lethal brain tumors. Tumor-associated proteases play an important role in glioma progression. Annexin A2 is overexpressed in many cancers and correlates with increased plasmin activity on the tumor cell surface, which ...
Stella E. Tsirka +7 more
core +1 more source
ABSTRACT This study investigates how phthalate exposure contributes to uterine fibroid (UF) development by studying the effects of the Mono‐(2‐ethyl‐5‐hydroxyhexyl) phthalate (MEHHP), a metabolite of Di(2‐ethylhexyl) phthalate, on myometrial stem cells (MMSCs).
Somayeh Vafaei +6 more
wiley +1 more source
Association of annexin A2 with cancer development (Review)
Annexin A2 (ANXA2) is a well-known calcium-dependent phospholipid binding protein widely distributed in the nucleus, cytoplasm and extracellular surface of various eukaryotic cells. It has been recognized as a pleiotropic protein affecting a wide range of molecular and cellular processes.
Xiao-Heng, Xu +4 more
openaire +3 more sources
Crystallographic Analysis of Calcium-Dependent Heparin Binding to Annexin A2
Journal of Biological Chemistry, 281, 31689–31695Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY.
Seaton, Barbara A. +6 more
core +1 more source

