Results 11 to 20 of about 55,065 (286)
Annexins induce curvature on free-edge membranes displaying distinct morphologies
Scientific Reports, 2018 Annexins are a family of proteins characterized by their ability to bind anionic membranes in response to Ca2+-activation. They are involved in a multitude of cellular functions including vesiculation and membrane repair.
Theresa Louise Boye +2 more
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Cell Reports, 2019 Summary: Uptake of apoptotic cells (ACs) by dendritic cells (DCs) and induction of a tolerogenic DC phenotype is an important mechanism for establishing peripheral tolerance to self-antigens.
Kevin Bode +9 more
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Annexins: players of single cell wound healing and regeneration
Communicative & Integrative Biology, 2019 Cell life is defined by a thin 4 nm plasma membrane, which separates the interior of a cell from its environment. Thus, disruption of the plasma membrane poses a critical risk to cells, which requires immediate repair to avoid uncontrolled osmotic lysis ...
Swantje Christin Häger +1 more
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Annexins in Translational Research: Hidden Treasures to Be Found
International Journal of Molecular Sciences, 2018 The vertebrate annexin superfamily (AnxA) consists of 12 members of a calcium (Ca2+) and phospholipid binding protein family which share a high structural homology.
Ursula Rescher
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Annexins—Coordinators of Cholesterol Homeostasis in Endocytic Pathways
International Journal of Molecular Sciences, 2018 The spatiotemporal regulation of calcium (Ca2+) storage in late endosomes (LE) and lysosomes (Lys) is increasingly recognized to influence a variety of membrane trafficking events, including endocytosis, exocytosis, and autophagy.
Carles Rentero +2 more
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Journal of Translational Medicine, 2019 Background Annexins are involved in vesicle trafficking, cell proliferation and apoptosis, but their functional mechanisms in ovarian cancer remain unclear.
Rui Gou +7 more
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Annexins as Overlooked Regulators of Membrane Trafficking in Plant Cells
International Journal of Molecular Sciences, 2017 Annexins are an evolutionary conserved superfamily of proteins able to bind membrane phospholipids in a calcium-dependent manner. Their physiological roles are still being intensively examined and it seems that, despite their general structural ...
Dorota Konopka-Postupolska, Greg Clark
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From brain to eye: Annexin A1 and A2 as a key mediator of retinal neuroinflammation in Parkinson’s and Alzheimer’s disease [PDF]
International Journal of Retina and VitreousThe retina, as an extension of the central nervous system, is highly susceptible to inflammatory and degenerative changes similar to those brain seen in Parkinson’s disease (PD) and Alzheimer’s disease (AD).
Luiz Philipe de Souza Ferreira +1 more
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Dysferlin Interacts with Annexins A1 and A2 and Mediates Sarcolemmal Wound-healing
Journal of Biological Chemistry, 2003 Mutations in the dysferlin gene cause limb girdle muscular dystrophy type 2B and Miyoshi myopathy. We report here the results of expression profile analyses and in vitro investigations that point to an interaction between dysferlin and the Ca2+ and lipid-
Bradley T Hyman, Robert H Brown
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Genome biology, 2004 SummaryAnnexins are traditionally thought of as calcium-dependent phospholipid-binding proteins, but recent work suggests a more complex set of functions.
S. Moss, R. O. Morgan
semanticscholar +3 more sources