Results 151 to 160 of about 21,238,471 (180)

A Decade-Old Atlas of TMEM (Transmembrane) Protein Family in Lung Cancer: Lessons Learnt and Future Directions. [PDF]

Int J Mol Sci
Zhang S, Cao G, Hu X, Chen C, Chen P.
europepmc   +1 more source

Evaluating the molecular function of zebrafish Anoctamin 1a. [PDF]

MicroPubl Biol
Dimatteo A, Stango N, Rich A, Sweet T.
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Advances in Anoctamin 1: A Potential New Drug Target in Medicinal Chemistry

Current Topics in Medicinal Chemistry, 2021
ANO1, anoctamin 1(also known as TMEM16A), is the molecular basis of calcium-activated chloride channels with ten transmembrane segments which are widely expressed in mammalian cells, including epithelial cells, vascular smooth muscle tissues, electro-excitatory cells, and some tumor cells.
Junjie Zhong, Xiaosheng Qu, Xin Cao
exaly   +3 more sources

Anoctamin 1 in secretory epithelia

Cell Calcium, 2014
Fluid and electrolyte releasing from secretory epithelia are elaborately regulated by orchestrated activity of ion channels. The activity of chloride channel at the apical membrane decides on the direction and the rate of secretory fluid and electrolyte.
Yongwoo, Jang, Uhtaek, Oh
openaire   +2 more sources

Anoctamin 1 expression in the mouse auditory brainstem

Cell and Tissue Research, 2014
Calcium-activated chloride channels (CaCCs) are involved in numerous physiological functions, including the epithelial movement of fluid. Anoctamin 1 (ANO1) has recently been cloned and characterized as a CaCC and is known to be expressed in various secretory epithelia and in nervous tissues such as the dorsal root ganglia and retina.
Sang Jae, Cho, Ji Hyun, Jeon, Do Ill, Chun, Sang Won, Yeo, In-Beom, Kim   +4 more
openaire   +2 more sources

Blockade of anoctamin-1 in injured and uninjured nerves reduces neuropathic pain

Brain Research, 2018
The aim of this study was to determine the participation of anoctamin-1 in 2 models of neuropathic pain in rats (L5/L6 spinal nerve ligation [SNL] and L5 spinal nerve transection [SNT]). SNL and SNT diminished withdrawal threshold in rats. Moreover, SNL up-regulated anoctamin-1 protein expression in injured L5 and uninjured L4 DRG whereas that it ...
Guadalupe Garcia, Vladimir A Martinez-Rojas, Norma Oviedo   +2 more
exaly   +3 more sources

Protons inhibit anoctamin 1 by competing with calcium

Cell Calcium, 2015
Cl(-) efflux through Ca(2+)-activated Cl(-) channels (CaCCs) in secretory epithelial cells plays a key role in the regulation of fluid secretion. The fluid and electrolyte secretion is closely related to intracellular pH. CaCCs have been known to be inhibited by intracellular acid.
Hyeyeon, Chun, Hawon, Cho, Jimi, Choi, Jesun, Lee, Sung Min, Kim, Hyungsup, Kim, Uhtaek, Oh   +6 more
openaire   +2 more sources

Role of the Ca2+-activated Cl- channels bestrophin and anoctamin in epithelial cells

Biological Chemistry, 2011
Two families of proteins, the bestrophins (Best) and the recently cloned TMEM16 proteins (anoctamin, Ano), recapitulate properties of Ca2+-activated Cl- currents.
Karl Kunzelmann, Patthara Kongsuphol, Krongkarn Chootip   +2 more
exaly   +2 more sources

Aerobic training in patients with anoctamin 5 myopathy and hyperckemia

Muscle and Nerve, 2014
INTRODUCTION: Anoctamin 5 deficiency has recently been defined to cause limb-girdle muscular dystrophy type 2L (LGMD2L) with pronounced hyperCKemia. No treatment interventions have been made so far in this condition.METHODS: In 6 patients with LGMD2L, we
Christoffer Rasmus Vissing, Nicolai Preisler, John Vissing   +2 more
exaly   +2 more sources