Results 101 to 110 of about 29,991,250 (177)

Cloning and Heterologous Expression of Anoctamin Isoforms [PDF]

, 2013
학위논문 (석사)-- 서울대학교 치의학대학원 : 치의학과, 2013. 2. Frank Hong Yu.Anoctamin1 (Ano1) has Ca2+-activated Cl- channel (CaCC) character which has an important role in salivation.
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core  

Proinflammatory Epstein–Barr Virus Antibody Functions Track with Disease Activity in Multiple Sclerosis

Annals of Neurology, Volume 100, Issue 3, Page 547-558, September 2026.
Objective Epstein–Barr virus (EBV) has been implicated in the pathogenesis of multiple sclerosis (MS). Elevated immunoglobulin G (IgG) titers against EBV nuclear antigen 1 (EBNA1) represent the most consistent serological marker of MS risk, with levels remaining persistently elevated following disease onset.
Malina Behrens, Paula Terroba‐Navajas, Eline A.J. Willemse, Sabine Schädelin, Manuel Comabella, Christian Münz, Gordan Lauc, Yannic Bartsch, Jens Kuhle, Jan D. Lünemann   +9 more
wiley   +1 more source

Effects of the Calcium-Activated Chloride Channel Inhibitors T16Ainh-A01 and CaCCinh-A01 on Cardiac Fibroblast Function

Cellular Physiology and Biochemistry, 2018
Background/Aims: Calcium-activated chloride channels (CaCCs) regulate numerous physiological processes including cell proliferation, migration, and extracellular matrix secretion. T16Ainh-A01 and CaCCinh-A01 are selective inhibitors of CaCCs.
Xiang-qin Tian, Ke-tao Ma, Xian-wei Wang, Yang Wang, Zhi-kun Guo, Jun-qiang  Si   +5 more
doaj   +1 more source

Proteomic Profiling of Myofiber Repair Annexins and Their Role in Duchenne Muscular Dystrophy

PROTEOMICS, Volume 26, Issue 9, Page 6-23, September 2026.
ABSTRACT Myofiber regeneration and membrane repair play crucial roles in maintaining the continuous physiological functioning of the neuromuscular system. A swift and efficient repair mechanism enables the rapid restoration of sarcolemmal integrity following cellular impairment in damaged skeletal muscles.
Paul Dowling, Dounia Bouragba, Elisa Negroni, Capucine Trollet, Margit Zweyer, Dieter Swandulla, Kay Ohlendieck   +6 more
wiley   +1 more source

Molecular Mechanisms of Electric Signals Generated at Corneal Wounds

The FASEB Journal, Volume 40, Issue 16, 31 August 2026.
Corneal injury triggers cell signaling (including calcium waves) leading to ion channel up‐regulation, increased ion pumping, and enhanced wound electric signals which stimulate wound healing. ABSTRACT Over 150 years ago, it was demonstrated that wounds produce electric fields and currents.
Brian Reid, Guillaume Luxardi, Min Zhao
wiley   +1 more source

Smooth muscle cell polycystin 1 (PKD1) is dispensable for physiological regulation of arterial contractility

The Journal of Physiology, Volume 604, Issue 15, Page 6348-6368, 1 August 2026.
Abstract figure legend Physiological functions of PKD1, a large transmembrane polycystin protein, are unclear. Previous results obtained using germline non‐specific knockout mice suggested that PKD1 regulates arterial smooth muscle cell contractility.
Angélica K. Bernardelli, Roberto B. Pontes, Alejandro Mata‐Daboin, Tessa A. C. Garrud, Ulrich C. Mbiakop, Marcos A. S. Leal, Dieniffer Peixoto‐Neves, Jonathan H. Jaggar   +7 more
wiley   +1 more source

TMEM16A-encoded anoctamin 1 inhibition contributes to chrysin-induced coronary relaxation

Biomedicine & Pharmacotherapy, 2020
Chrysin, a natural flavonoid available in honey, propolis and medicinal plants, has been shown to be vasorelaxant in some vascular beds. Proper intake of an alimental vasodilator as a food additive may be a promising strategy for prevention and treatment of coronary spasmodic disorders.TMEM16A-encoded anoctamin 1 (ANO1), a Ca2+ activated Cl- channel ...
Guijin, Ma, Jiangtao, Zhang, Xiaomin, Yang, Pengmei, Guo, Xiaomin, Hou, Yanying, Fan, Yu, Liu, Mingsheng, Zhang   +7 more
openaire   +2 more sources

Relationship Between Central Sensitization and Genetic Polymorphisms—A Case–Control Study in Fibromyalgia

European Journal of Pain, Volume 30, Issue 6, July 2026.
ABSTRACT Background Fibromyalgia is a syndrome characterised by widespread chronic pain, which is believed to be mediated by a state of central sensitisation (CS). Based on the hypothesis that CS itself could have genetic determinants, our aim was to further explore this pathway.
Nicolas Macian, Christian Dualé, Marine Delay, Vincent Leray, Bruno Pereira, Yoan Renaud, Yvonne Gloor, Jules Desmeules, Gisèle Pickering   +8 more
wiley   +1 more source

Anoctamin‐1 channel localization in excitable domains of the heart (893.23)

The FASEB Journal, 2014
Calcium‐activated chloride (Cl Ca ) currents are widely distributed in cardiac tissues and have been implicated to play a role in cardiac physiology and pathophysiology. Anoctamin‐1 (Ano1) is a membrane protein that functions as a Cl Ca channel and has ...
Fiona Britton, Kate O'Driscoll, William Hatton   +2 more
openaire   +1 more source

Anoctamin 2/TMEM16B: A calcium-activated chloride channel in olfactory transduction [PDF]

, 2012
In vertebrate olfactory transduction, a Ca2+-dependent Cl- efflux greatly amplifies the odorant response. The binding of odorants to receptors in the cilia of olfactory sensory neurons activates a transduction cascade that involves the opening of cyclic ...
Pifferi S., Cenedese V., Menini A.
core   +1 more source