Results 111 to 120 of about 29,991,250 (177)

Salivary Extracellular Vesicles: Paradigm Shift in Liquid Biopsy Diagnostics

Journal of Extracellular Biology, Volume 5, Issue 7, July 2026.
ABSTRACT Extracellular vesicles (EVs), lipid bilayer nanoparticles released by virtually all cells, serve as essential messengers for intercellular communication. Due to their involvement in several pathophysiological processes, EVs have recently gained considerable attention as potentially diagnostic and prognostic biomarkers for various illnesses ...
Kwanele Xulu, Usri H. Ibrahim, Irene Mackraj, Carola Niesler   +3 more
wiley   +1 more source

Characterization of TMEM16F-Specific Affibodies and Their Cellular Effects

Membranes
The TMEM16 (Anoctamin) family comprises a group of transmembrane proteins involved in diverse physiological processes, including ion transport and phospholipid scrambling.
Eunyoung Kim, Jinho Bang, Sunghyun Kim, Byoung-Cheol Lee   +3 more
doaj   +1 more source

Mechanisms underlying gastric antral slow waves – a human perspective

The Journal of Physiology, EarlyView.
Dirk F. van Helden
wiley   +1 more source

Anoctamin pharmacology

: TMEM16 proteins, also known as anoctamins, are a family of ten membrane proteins with various tissue expression and subcellular localization. TMEM16A (anoctamin 1) is a plasma membrane protein that acts as a calcium-activated chloride channel.
Galietta, Luis Juan Vicente, Genovese, Michele   +1 more
core   +1 more source

Anoctamin 1 is Apically Expressed on Thyroid Follicular Cells and Contributes to ATP- and Calcium-Activated Iodide Efflux

Cellular Physiology and Biochemistry, 2014
Background/Aims: Iodide efflux from thyroid cells into the follicular lumen is essential for the synthesis of thyroid hormones, however, the pathways mediating this transport have only been partially identified.
Carmela Iosco, Cristina Cosentino, Laura Sirna, Roberta Romano, Silvia Cursano, Alessandra Mongia, Giampaolo Pompeo, Julie di Bernardo, Claudio Ceccarelli, Giovanni Tallini, Kerry J. Rhoden   +10 more
doaj   +1 more source

Control of Lung Myofibroblast Activation by Anoctamine-1 [PDF]

C57. EXTRACELLULAR MATRIX AND SUBCELLULAR DYNAMICS IN COMPLEX LUNG DISEASE, 2020
N.O. Dulin, E.B. Reed, P.S. Woods, G.M. Mutlu   +3 more
openaire   +1 more source

Control of Ion Transport by Tmem16a Expressed in Murine Intestine

Frontiers in Physiology, 2019
Cl– secretion by the human and murine intestinal epithelium occurs through the cystic fibrosis transmembrane conductance regulator (cftr). However, the Ca2+ activated Cl– channel Tmem16a was shown to contribute to Cl– secretion, mainly, but not ...
Karl Kunzelmann, Raquel Centeio, Podchanart Wanitchakool, Inês Cabrita, Roberta Benedetto, Tultul Saha, Kazi Mirajul Hoque, Kazi Mirajul Hoque, Rainer Schreiber   +8 more
doaj   +1 more source

The scramblase Anoctamin 9 controls the immune response of lymphocytes

Functional data from submission:"The scramblase Anoctamin 9 controls the immune response of ...
Kunzelmann, Karl
core   +1 more source

Anoctamin 6 mediates effects essential for innate immunity downstream of P2X7 receptors in macrophages

, 2015
Purinergic P2X7 receptors (P2X7R) are fundamental to innate immune response. In macrophages, transient stimulation of P2X7R activates several transport mechanisms and induces the scrambling of phospholipids with subsequent membrane blebbing and apoptosis.
Romao, Ana M., Kmit, Arthur, Wanitchakool, Podchanart, Ousingsawat, Jiraporn, Kunzelmann, Karl, Jantarajit, Walailak, Schreiber, Rainer   +6 more
core   +1 more source

Anoctamin Calcium-Activated Chloride Channels May Modulate Inhibitory Transmission in the Cerebellar Cortex. [PDF]

, 2015
Calcium-activated chloride channels of the anoctamin (alias TMEM16) protein family fulfill critical functions in epithelial fluid transport, smooth muscle contraction and sensory signal processing.
Daniel Parthier, Stephan Frings, Weiping Zhang, Frank Möhrlen, Steffen Schmelzeisen   +4 more
core   +1 more source