Results 81 to 90 of about 2,953 (148)
Mechanisms underlying gastric antral slow waves – a human perspective
The Journal of Physiology, EarlyView.
Dirk F. van Helden
wiley +1 more source
Neuroinflammation as a result of non‐neurotropic herpesvirus infection
Atypical memory B cells (ABCs) might stimulate autoreactive T cells to cause neuroinflammation and CNS myeloid cell activation during MS. Abstract The non‐neurotropic Epstein Barr virus (EBV) has been suggested to initiate the prodromal phase of multiple sclerosis (MS), often years before the first clinical symptoms. This review discusses mechanisms by
Christian Münz
wiley +1 more source
Cell-specific mechanisms of TMEM16A Ca2+-activated chloride channel in cancer
TMEM16A (known as anoctamin 1) Ca2+-activated chloride channel is overexpressed in many tumors. TMEM16A overexpression can be caused by gene amplification in many tumors harboring 11q13 amplification.
Hui Wang +6 more
doaj +1 more source
Anoctamin‐1 channel localization in excitable domains of the heart (893.23)
Calcium‐activated chloride (Cl Ca ) currents are widely distributed in cardiac tissues and have been implicated to play a role in cardiac physiology and pathophysiology. Anoctamin‐1 (Ano1) is a membrane protein that functions as a Cl Ca channel and has ...
Fiona Britton +2 more
openaire +1 more source
Interstitial cells of Cajal (ICCs) play a key role in gastrointestinal smooth muscle contractions, but their relationship with anal canal function in advanced haemorrhoidal disease (HD) remains poorly understood. This study uses deep neural network (DNN)
Inese Fišere +3 more
doaj +1 more source
How Epstein–Barr Virus Drives Multiple Sclerosis: New Mechanisms and Therapeutic Lessons
MedComm, Volume 7, Issue 7, July 2026.
Dan Liu, Wenhui Fan, Pengtao Jiao
wiley +1 more source
Background/Aims: Calcium-activated chloride channels (CaCCs) regulate numerous physiological processes including cell proliferation, migration, and extracellular matrix secretion. T16Ainh-A01 and CaCCinh-A01 are selective inhibitors of CaCCs.
Xiang-qin Tian +5 more
doaj +1 more source
Differential expression of anoctamin 1 in human epithelial ovarian cancer.
Epithelial ovarian cancer (EOC) is the most lethal gynecologic cancer (1). We performed discovery of genes associated with epithelial ovarian cancer and of the high-grade serous ovarian cancer (HGSC) subtype, using published and public microarray data (2, 3) to compare global gene expression profiles of normal ovary or fallopian tube with that of ...
openaire +2 more sources
Background/Aims: Iodide efflux from thyroid cells into the follicular lumen is essential for the synthesis of thyroid hormones, however, the pathways mediating this transport have only been partially identified.
Carmela Iosco +10 more
doaj +1 more source
Characterization of TMEM16F-Specific Affibodies and Their Cellular Effects
The TMEM16 (Anoctamin) family comprises a group of transmembrane proteins involved in diverse physiological processes, including ion transport and phospholipid scrambling.
Eunyoung Kim +3 more
doaj +1 more source

