Results 191 to 200 of about 1,056,606 (342)

Caffeine Mitigates Adenosine-Mediated Angiogenic Properties of Choroidal Endothelial Cells Through Antagonism of A₁ Adenosine Receptor and PI3K-AKT Axis. [PDF]

Cells
Park S, Song YS, Feng X, Sorenson CM, Sheibani N.   +4 more
europepmc   +1 more source

Non-Peptide Cholecystokinin-B/Gastrin Receptor Antagonists Based on Bicyclic, Heteroaromatic Skeletons

, 1996
S. Barret Kalindjian, Ildiko M. Buck, Jonathan M. R. Davies, David J. Dunstone, Martin L. Hudson, Caroline M. R. Low, Iain M. McDonald, Michael J. Pether, Katherine I. M. Steel, Matthew J. Tozer, Jeremy G. Vinter   +10 more
openalex   +1 more source

Effects of the p-selectin antagonist inclacumab on myocardial damage according to the time interval between infusion and percutaneous coronary intervention [PDF]

, 2013
Valérie Duchatelle, Philippe L. L’Allier, J.-F. Tanguay, Thibaut Petroni, Sheri L. Robb, D. C. Johnson, Daniel Cournoyer, Marie Claude Guertin, Sheri Wright, Jean‐Claude Tardif   +9 more
openalex   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

CXCR4 antagonism corrects neutrophil abnormalities and reduces pneumonia severity in a pharmacological mouse model of CXCR2 loss-of-function-mediated neutropenia. [PDF]

Front Immunol
Nguyen CH, Zmajkovicova K, Sekirnik A, Taplin S, Defontis M, Bledsoe JR, Taveras AG, Karlsson L, Johnson R.   +8 more
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

A prospective cohort study on progestin-primed ovarian stimulation vs. GnRH antagonist in IVF-ICSI cycles: effects on clinical pregnancy and neonatal outcomes. [PDF]

J Ovarian Res
Yang C, Chen Q, Shen X, Guo H, Lin J, Lu X, Wen X, Zhu Q, Chai W.   +8 more
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Baishaoluoshi Decoction Mitigates Post-Stroke Spasticity by Targeting Synaptic Plasticity Through the Nogo-A/NgR Signaling Pathway. [PDF]

Brain Behav
Sun X, Zeng S, Lin S, Wu L, Tang X, Zhu J, Zhang Y, Li L, Chen Z, Deng X, Wu D, Xie L.   +11 more
europepmc   +1 more source

4-(ω-(Alkyloxy)alkyl)-1H-imidazole Derivatives as Histamine H₃Receptor Antagonists/Agonists

, 2004
Galina Meier, Michael Krause, Annette Hüls, Xavier Ligneau, Heinz H. Pertz, Jean‐Michel Arrang, C. Robin Ganellin, Jean‐Charles Schwartz, Walter Schunack, Holger Stark   +9 more
openalex   +1 more source