Results 221 to 230 of about 1,541,253 (387)

Tolvaptan, a selective oral vasopressin V2-receptor antagonist, for hyponatremia.

New England Journal of Medicine, 2006
R. Schrier, P. Gross, M. Gheorghiade, T. Berl, J. Verbalis, F. Czerwiec, C. Orlandi   +6 more
semanticscholar   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Thrombin induces degradation of murine intervertebral discs via angiogenesis and M1-like polarization of macrophages. [PDF]

Sci Rep
Tatsuno R, Ando T, Fujimaki T, Takayama Y, Ohba T, Haro H.   +5 more
europepmc   +1 more source

Studies on Nucleic Acid Antagonists. I. Syntheses of 5-Phenylazopyrimidines.

, 1959
Kuniyoshi Tanaka, Einosuke Omura, Toshio Sugawa, Yasushi Sanno, Yukio Ando, Kin-ichi Imai, Minoru Kawashima   +6 more
openalex   +2 more sources

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Evaluation of the effects of the Stop GnRH agonist with the letrozole protocol in poor ovarian responders: ABOTH randomized controlled trial. [PDF]

JBRA Assist Reprod
Saharkhiz N, Hosseini S, Kazemi M, Majdi L, Esmaeili S, Nemati M, Hosseinzadeh M, Zarisfi Z.   +7 more
europepmc   +1 more source

3. Antagonistic Effects of Calabar Bean and Atropia [PDF]

R KLEINWACHTE
openalex   +1 more source

Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran

Cell, 2007
Ho Min Kim, B. Park, Jung-In Kim, Sung Eun Kim, Judong Lee, Se Cheol Oh, P. Enkhbayar, N. Matsushima, Hayyoung Lee, O. Yoo, Jie-Oh Lee   +10 more
semanticscholar   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Utility of GnRH Agonists before embryo transfer in women with adenomyosis: Systematic review and meta-analysis. [PDF]

JBRA Assist Reprod
González-Comadran M, Olmos EA, Mariño MAA, Vizcaíno MAC.   +3 more
europepmc   +1 more source