Results 251 to 260 of about 1,481,945 (415)

Relationship Between Estradiol Levels Measured on the Initiation Day of GnRH Antagonist Treatment and Pregnancy Outcomes in Patients Receiving the Antagonist Protocol. [PDF]

Medicina (Kaunas)
Karaçin P, Özelçi R, Kumcu E, Kaya Kaplanoğlu D, Dilbaz S, Üstün Y.   +5 more
europepmc   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Correction: Impact of GnRH antagonist pretreatment on oocyte yield after ovarian stimulation: A retrospective analysis. [PDF]

PLoS One
PLOS One Staff.
europepmc   +1 more source

ISOLATION OF THE PHYTOPATHOGENIC TOXIN OF PSEUDOMONAS TABACI, AN ANTAGONIST OF METHIONINE

, 1952
D. W. Woolley, Ross B. Pringle, Armin Braun   +2 more
openalex   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

The Contact Allergen Methylisothiazolinone (MIT) is a Potent Activator of the TRPA1 Ion Channel. [PDF]

Pharmacol Res Perspect
Mäki-Opas I, Luostarinen S, Hämäläinen M, Muraki K, Moilanen E.   +4 more
europepmc   +1 more source

Clinical trial with a beta-receptor antagonist (propranolol) in parkinsonism. [PDF]

, 1965
R. R. Strang
openalex   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Progestin-primed ovarian stimulation for oocyte cryopreservation in patients with nonmedical indications: a case-control study. [PDF]

Reprod Biol Endocrinol
Sounigo O, Cohen Aloro L, Grynberg M, Becquart C, Majer M, Puy V, Sifer C, Vinolas C, Eustache F, Hesters L, Mayeur A, Cedrin-Durnerin I, Sonigo C, Peigné M.   +13 more
europepmc   +1 more source

Cholinergic agonist-antagonist interactions on neocortical and limbic EEG activation [PDF]

, 1967
Yamamoto Kjen-Ichi, Edward F. Domino
openalex   +1 more source