Results 21 to 30 of about 20,097 (237)

Sub-lethal doses of albendazole induce drug metabolizing enzymes and increase albendazole deactivation in Haemonchus contortus adults

Veterinary Research, 2020
The efficacy of anthelmintic therapy of farm animals rapidly decreases due to drug resistance development in helminths. In resistant isolates, the increased expression and activity of drug-metabolizing enzymes (DMEs), e.g.
Pavlína Kellerová, Lucie Raisová Stuchlíková, Petra Matoušková, Karolína Štěrbová, Jiří Lamka, Martina Navrátilová, Ivan Vokřál, Barbora Szotáková, Lenka Skálová   +8 more
doaj   +1 more source

Study of triclabendazole effects on Fasciola hepatica’s life-supporting organs, spines and suckers responsible for stable position of the parasite in the host

Российский паразитологический журнал, 2021
The purpose of the research is to study triclabendazole effects on the Fasciola’s life-supporting organs, spines and suckers which are responsible for stable position of the parasite in the host.Materials and methods.
O. I. Bibik, I. A. Arkhipov
doaj   +1 more source

Modifcation of anthelmintic drugs by nanotechnology (review)

Российский паразитологический журнал, 2022
The purpose of the research is to analyze and summarize the literature data and the results of our own studies on the use of drug delivery systems and methods for increasing the solubility and efcacy of anthelmintic drugs.Helminthoses are one of the most
A. I. Varlamova, I. A. Arkhipov, S. S. Khalikov, M. V. Arisov   +3 more
doaj   +1 more source

Tannins Can Have Direct Interactions with Anthelmintics: Investigations by Isothermal Titration Calorimetry

Molecules, 2023
Plant tannins are known for their anthelmintic and antiparasitic activities and have been increasingly studied to battle the ever-growing problem of anthelmintic resistance.
Mimosa Sillanpää, Marica T. Engström, Petri Tähtinen, Rebecca J. Green, Jarmo Käpylä, Anu Näreaho, Maarit Karonen   +6 more
doaj   +1 more source

Oxfendazole flukicidal activity in pigs [PDF]

, 2014
Although oxfendazole (OFZ) is a well know broad-spectrum benzimidazole anthelmintic, the assessment of its potential trematodicidal activity remains unexplored.
Alvarez, Luis Ignacio, Cabrera, Maria, Cantón, Candela, Ceballos, Laura, Donedeu, Meritxell, Hoban, Cristian, Lanusse, Carlos Edmundo, Moreno, Laura Susana, Ortiz, Pedro, Terrones, Susana   +9 more
core   +1 more source

Histopathological Changes of Egg Cells in the Uterine of Ascaridia galli after Treatment with Extract of Veitchia merrillii Nuts

Majalah Obat Tradisional, 2017
The aim of the study was to observe the histopathological changes of the entire egg cells in the uterine of Ascaridia galli worms treated with crude ethanolic extract of Veitchia merrillii nuts.
Ummu Balqis, Muslina Muslina, Muhammad Hambal, Farida Athaillah, Muttaqien Muttaqien, Azhar Azhar, Ismail Ismail, Rastina Rastina, Eliawardani Eliawardani, Abdul Harris, Abdullah Hamzah, Henni Vanda, Darmawi Darmawi   +12 more
doaj   +1 more source

In vitro and in vivo anthelmintic efficacy of plant cysteine proteinases against the rodent gastrointestinal nematode, Trichuris muris [PDF]

, 2006
We examined the mechanism of action and compared the anthelmintic efficacy of cysteine proteinases from papaya, pineapple, fig, kiwi fruit and Egyptian milkweed in vitro using the rodent gastrointestinal nematode Heligmosomoides polygyrus.
Behnke, J.M., Buttle, D.J., Duce, I.R., Lowe, A.E., Stepek, G.   +4 more
core   +3 more sources

Three Small Molecule Entities (MPK18, MPK334 and YAK308) with Activity against Haemonchus contortus In Vitro

Molecules, 2021
Due to widespread multi-drug resistance in parasitic nematodes of livestock animals, there is an urgent need to discover new anthelmintics with distinct mechanisms of action.
Aya C. Taki, Abdul Jabbar, Thomas Kurz, Beate Lungerich, Guangxu Ma, Joseph J. Byrne, Marc Pflieger, Yodita Asfaha, Fabian Fischer, Bill C. H. Chang, Brad E. Sleebs, Robin B. Gasser   +11 more
doaj   +1 more source

Management of Rat Lungworm Disease (Neuroangiostrongyliasis) Using Anthelmintics: Recent Updates and Recommendations

Pathogens, 2022
While there have been legitimate concerns in the past regarding the use of anthelmintics for the management of neuroangiostrongyliasis (rat lungworm disease), recent studies demonstrate that they can be considered safe and efficacious, particularly ...
John Jacob, Argon Steel, Kathleen Howe, Susan Jarvi   +3 more
doaj   +1 more source

Anthelmintic action of plant cysteine proteinases against the rodent stomach nematode, Protospirura muricola, in vitro and in vivo [PDF]

, 2007
Cysteine proteinases from the fruit and latex of plants, including papaya, pineapple and fig, were previously shown to have a rapid detrimental effect, in vitro, against the rodent gastrointestinal nematodes, H eligmosomoides polygyrus (which is found in
Behnke, J.M., Buttle, D.J., Duce, I.R., Lowe, A.E., Stepek, G.   +4 more
core   +3 more sources